Ministry of Education Key Laboratory of Cell Activities and Stress Adaptations, School of Life Sciences, Lanzhou University, Lanzhou 730000, China.
Guangdong Provincial Key Laboratory of Plant Adaptation and Molecular Design, School of Life Sciences, Guangzhou University, Guangzhou 510006, China.
Int J Mol Sci. 2024 Jul 25;25(15):8111. doi: 10.3390/ijms25158111.
Brassinosteroids (BRs) are an essential group of plant hormones regulating numerous aspects of plant growth, development, and stress responses. BRI1, along with its co-receptor BAK1, are involved in brassinosteroid sensing and early events in the BR signal transduction cascade. Mutational analysis of a particular gene is a powerful strategy for investigating its biochemical role. Molecular genetic studies, predominantly in , but progressively in numerous other plants, have identified many mutants of the gene and its orthologs to gain insight into its structure and function. So far, the plant kingdom has identified up to 40 alleles in Arabidopsis and up to 30 orthologs in different plants. These alleles exhibit phenotypes that are identical in terms of development and growth. Here, we have summarized alleles in Arabidopsis and its orthologs present in various plants including monocots and dicots. We have discussed the possible mechanism responsible for the specific allele. Finally, we have briefly debated the importance of these alleles in the research field and the agronomically valuable traits they offer to improve plant varieties.
油菜素内酯（BRs）是一类重要的植物激素，调节植物生长、发育和应激反应的多个方面。BRI1 及其共受体 BAK1 参与油菜素内酯的感应和 BR 信号转导级联的早期事件。对特定基因的突变分析是研究其生化作用的有力策略。分子遗传学研究，主要在 ，但在越来越多的其他植物中，已经鉴定出许多该基因及其同源物的突变体，以深入了解其结构和功能。到目前为止，植物界已经在拟南芥中鉴定出多达 40 个等位基因，在不同的植物中鉴定出多达 30 个同源物。这些等位基因在发育和生长方面表现出相同的表型。在这里，我们总结了拟南芥中的 等位基因及其在包括单子叶植物和双子叶植物在内的各种植物中的同源物。我们讨论了负责特定等位基因的可能机制。最后，我们简要讨论了这些等位基因在研究领域的重要性以及它们提供的改善植物品种的农艺有价值的性状。
