Cerqueira Thaís Braga, Imoto Renata Robl, Muzzolon Mariana, de Carvalho Vânia Oliveira
Programa de Pós-Graduação em Dermatologia Pediátrica, Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
Programa de Pós-Graduação em Saúde da Criança e do Adolescente, Complexo do Hospital de Clínicas, Universidade Federal do Paraná (UFPR), Curitiba, PR, Brazil.
J Pediatr (Rio J). 2025 Jan-Feb;101(1):67-73. doi: 10.1016/j.jped.2024.07.003. Epub 2024 Aug 8.
To evaluate the effect of text messages with information about atopic dermatitis (AD) on the quality of life (QoL) of children and their caregivers and on the severity of the disease.
Researcher-blinded randomized controlled clinical trial. The experimental group (EG) received messages about AD and the control group (CG) about general health. A total of 56 children under 15 years of age and their caregivers, allocated to the CG and EG, were assessed on admission, after one month, and after four months. Improvement in QoL was measured by the Children's Dermatology Life Quality Index (CDLQI), the Infants' Dermatitis Quality of Life Index (IDQOL), and the Dermatitis Family Impact Questionnaire (DFIQ), and improvement in the severity of AD by the Scoring of Atopic Dermatitis (SCORAD) and the Eczema Area and Severity Index (EASI).
Median age was of nine years, 33 (58.9 %) were girls. The CG and EG had similar results, except for the higher frequency of mild AD in the CG and moderate/severe AD in the EG-these severity categories were kept grouped together. Regarding mild and moderate/severe AD in the EG, the SCORAD score decreased (p = 0.03 and p < 0.001). The EASI in both groups showed a significant reduction (mild AD: CG: p = 0.01, EG: p = 0.04; moderate/severe AD: CG: p = 0.05, EG: p = 0.02). The QoL of children and caregivers improved only in the EG (p = 0.01). Intergroup analysis showed no differences.
The improvement in the severity of AD in both groups suggests the positive effects of educational interventions in general, not only those specific to the disease.
评估含有特应性皮炎(AD)相关信息的短信对儿童及其照顾者生活质量(QoL)以及疾病严重程度的影响。
研究者设盲的随机对照临床试验。实验组(EG)接收关于AD的短信,对照组(CG)接收关于一般健康的短信。共有56名15岁以下儿童及其照顾者被分配至CG和EG组,在入院时、1个月后和4个月后进行评估。通过儿童皮肤病生活质量指数(CDLQI)、婴儿皮炎生活质量指数(IDQOL)和皮炎家庭影响问卷(DFIQ)来衡量QoL的改善情况,通过特应性皮炎评分(SCORAD)和湿疹面积及严重程度指数(EASI)来衡量AD严重程度的改善情况。
中位年龄为9岁,33名(58.9%)为女孩。CG和EG组结果相似,但CG组轻度AD的发生率较高,EG组中度/重度AD的发生率较高——这些严重程度类别合并在一起。关于EG组中的轻度和中度/重度AD,SCORAD评分降低(p = 0.03和p < 0.001)。两组的EASI均显著降低(轻度AD:CG:p = 0.01,EG:p = 0.04;中度/重度AD:CG:p = 0.05,EG:p = 0.02)。仅EG组儿童及其照顾者的QoL得到改善(p = 0.01)。组间分析无差异。
两组AD严重程度的改善表明一般教育干预具有积极作用,不仅是针对该疾病的特定干预。