富含ω-3 脂肪酸的饮食对合并抑郁的鳞状细胞肺癌患者生活质量的影响：一项回顾性研究。
The Impact of a Diet Rich in Omega-3 Fatty Acids on the Quality of Life of Patients with Squamous Cell Lung Cancer and Comorbid Depression: A Retrospective Study.
机构信息
Outpatient Operating Room, Hongqi Hospital Affiliated to Mudanjiang Medical University, 157011 Mudanjiang, Heilongjiang, China.
Department of Pediatrics, Hongqi Hospital Affiliated to Mudanjiang Medical University, 157011 Mudanjiang, Heilongjiang, China.
出版信息
Actas Esp Psiquiatr. 2024 Aug;52(4):445-452. doi: 10.62641/aep.v52i4.1654.
BACKGROUND
Lung cancer is a significant health concern, and is often accompanied by comorbid depression, leading to worsened prognosis and decreased quality of life for patients. This study aimed to investigate the potential influence of a diet rich in Omega-3 fatty acids on the quality of life of patients with squamous cell lung cancer and comorbid depression.
METHODS
A retroactive analysis of clinical information from patients with squamous cell lung cancer and comorbid depression admitted to Hongqi Hospital Affiliated to Mudanjiang Medical University from June 2022 to June 2023 was conducted. The patients were classified into two groups on the basis of different dietary care approaches: the Routine Dietary Group and the Omega-3 Fatty Acids Group. Baseline characteristics, pulmonary function tests, dietary intake, depression scoring, and quality of life scores were compared between the two groups.
RESULTS
103 patients in total were included, with 51 in the Routine Dietary Group and 52 in the Omega-3 Fatty Acids Group. The Omega-3 Fatty Acids Group exhibited significantly higher ingestion of Omega-3 fatty acids in comparison with the Routine Dietary Group (3.15 ± 0.64 g/day vs. 2.93 ± 0.28 g/day, p = 0.022). Despite similar baseline pulmonary function tests, patients in the Omega-3 Fatty Acids Group showed significantly higher scores in physical (70.17 ± 4.81 vs. 68.18 ± 5.03, p = 0.043) and emotional (71.29 ± 4.58 vs. 69.38 ± 4.25, p = 0.030) functioning, as well as lower scores in insomnia (27.41 ± 4.51 vs. 29.34 ± 4.21, p = 0.027) and constipation (7.34 ± 1.66 vs. 8.43 ± 3.36, p = 0.040).
CONCLUSION
The study provided insights into the potential impact of a diet rich in Omega-3 fatty acids on the quality of life of patients with squamous cell lung cancer and complicating depression, suggesting that dietary interventions emphasizing Omega-3 fatty acids may be conducive to improving physical and emotional functioning, as well as symptom management, in this patient population.
背景
肺癌是一个严重的健康问题，常伴有合并症抑郁，导致患者预后恶化和生活质量下降。本研究旨在探讨富含欧米伽-3 脂肪酸的饮食对合并抑郁的肺鳞癌患者生活质量的潜在影响。
方法
回顾性分析 2022 年 6 月至 2023 年 6 月在牡丹江医学院红旗医院住院的肺鳞癌合并抑郁患者的临床资料。根据不同的饮食护理方法，将患者分为常规饮食组和欧米伽-3 脂肪酸组：两组患者的基线特征、肺功能检查、饮食摄入、抑郁评分和生活质量评分。
结果
共纳入 103 例患者，其中常规饮食组 51 例，欧米伽-3 脂肪酸组 52 例。与常规饮食组相比，欧米伽-3 脂肪酸组的欧米伽-3 脂肪酸摄入量明显更高（3.15 ± 0.64 g/d 比 2.93 ± 0.28 g/d，p = 0.022）。尽管两组患者的肺功能检查基线相似，但欧米伽-3 脂肪酸组患者的身体（70.17 ± 4.81 比 68.18 ± 5.03，p = 0.043）和情绪（71.29 ± 4.58 比 69.38 ± 4.25，p = 0.030）功能评分更高，失眠（27.41 ± 4.51 比 29.34 ± 4.21，p = 0.027）和便秘（7.34 ± 1.66 比 8.43 ± 3.36，p = 0.040）评分更低。
结论
本研究探讨了富含欧米伽-3 脂肪酸的饮食对合并抑郁的肺鳞癌患者生活质量的潜在影响，提示富含欧米伽-3 脂肪酸的饮食干预可能有助于改善这一患者群体的身体和情绪功能以及症状管理。
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