Balani Abhishek, Tandon Jaishree, Kharsan Vinay, Karan Abhishek, Mazhar Heena, Awasthy Arunima
Department of Oral and Maxillofacial Surgery, New Horizon Dental College and Research Institute, Sakri, Bilaspur, Chhattisgarh, India.
Bioinformation. 2024 Jun 30;20(6):600-604. doi: 10.6026/973206300200600. eCollection 2024.
Bone transplant with osteopromotive elements - such as herbal extracts - that promote the creation of new boneis of interest to dentists. Hence, we compared the bone loss around dental implants while placing platelet rich fibrin (PRF) scaffold alone and PRF scaffold with simvastatin (SIM) and PRF scaffold with Moringaoleifera (MO). There were thirty six patients total. A total of 36 implants, or twelve implants in all three categories, were the estimated sample size. Category 1: PRF scaffolds alone. Category 2: PRF scaffolds with SIM. Category 3: PRF scaffolds with MO. Alteration in the bones were measured with CBCT. It was observed that there was decreased loss of crestal bone in PRF+ SIM and PRF+MO as compared to PRF alone. The use of herbal osteopromotive agents like simvastitin and Moringaoleifera along with PRF scaffolds can be effective in reducing bone loss around dental implants.
含有促进新骨生成的骨诱导成分（如草药提取物）的骨移植对牙医来说很有吸引力。因此，我们比较了单独植入富血小板纤维蛋白（PRF）支架、PRF支架与辛伐他汀（SIM）联用以及PRF支架与辣木（MO）联用情况下牙种植体周围的骨质流失情况。总共有36名患者。估计样本量为总共36颗种植体，即三类中每类各12颗种植体。第1类：单独使用PRF支架。第2类：PRF支架与SIM联用。第3类：PRF支架与MO联用。使用锥形束计算机断层扫描（CBCT）测量骨质变化。观察到，与单独使用PRF相比，PRF + SIM组和PRF + MO组的牙槽嵴骨丢失减少。将辛伐他汀和辣木等草药骨诱导剂与PRF支架一起使用可有效减少牙种植体周围的骨质流失。
