Matteelli A, Mkrtchyan Z, Masini T, Hovhannesyan A, Kuchukhidze G, Ahmedov S, Kerndt P, Rossi L, Yedilbayev A, Falzon D, Dadu A
Institute of Infectious and Tropical Diseases, WHO Collaborating Centre for Tuberculosis Prevention, University of Brescia, Brescia, Italy.
London School of Hygiene & Tropical Medicine, London, UK.
IJTLD Open. 2024 Aug 1;1(8):349-354. doi: 10.5588/ijtldopen.24.0350. eCollection 2024 Aug.
TB preventive treatment (TPT) is the primary available healthcare intervention to reduce the risk of progression from TB infection to TB disease. The WHO Regional Office for Europe established the European Prevention and Systematic Screening Initiative to End TB (PASS) to scale up activities related to the programmatic management of TPT. In the absence of a system to measure and monitor preventive activities, a baseline assessment survey was carried out to provide a reference to monitor the scale-up of the intervention.
This was a semi-structured survey including 52 questions that was developed, implemented in the WHO-hosted LimeSurvey data form and sent to focal points in the 55 countries and territories in the European Region between September and October 2023. The questions covered TPT, systematic screening and infection prevention and control.
A total of 28 questionnaires were returned, corresponding to an overall 51% response rate. Most national policies for TPT and TB screening are in line with the latest WHO guidelines. However, implementation of TB screening, prevention, and infection control activities is lagging. Results are presented separately for high-priority and low-priority countries.
The survey identified several important areas that the PASS initiative will focus on to accelerate efforts towards reaching the targets set at the 2027 UN High-Level Meeting on TB for preventive therapy in the European Region. This will require a massive scale-up of efforts and larger investments, as well as coordinated approaches and interventions across the 'cascade' of prevention, from the identification of target populations to the completion of treatment.
结核病预防性治疗(TPT)是降低从结核感染进展为结核病风险的主要现有医疗保健干预措施。世界卫生组织欧洲区域办事处设立了欧洲终结结核病预防和系统筛查倡议(PASS),以扩大与TPT规划管理相关的活动。在缺乏衡量和监测预防活动的系统的情况下,开展了一项基线评估调查,以提供监测干预措施扩大规模的参考。
这是一项半结构化调查,包括52个问题,该调查在世界卫生组织托管的LimeSurvey数据表单中制定、实施,并于2023年9月至10月发送给欧洲区域55个国家和地区的联络点。问题涵盖TPT、系统筛查以及感染预防和控制。
共返回28份问卷,总体回复率为51%。大多数国家的TPT和结核病筛查政策符合世界卫生组织的最新指南。然而,结核病筛查、预防和感染控制活动的实施滞后。分别列出了高优先级和低优先级国家的结果。
该调查确定了PASS倡议将重点关注的几个重要领域,以加快努力实现2027年联合国结核病问题高级别会议为欧洲区域预防性治疗设定的目标。这将需要大规模扩大努力和增加投资,以及在从确定目标人群到完成治疗的整个预防“级联”过程中采取协调一致的方法和干预措施。