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慢性局部使用氯胺酮期间与早期炎症性肠病相关的氯胺酮诱导的硬化性胆管炎

Ketamine-Induced Sclerosing Cholangitis Associated With Early Inflammatory Bowel Disease During Chronic Topical Ketamine Use.

作者信息

Lake-Bakaar Gerond, Milgrom Benjamin, Kulig Clark, Sotelo Andrea K, Speirs Joselle, Meihofer Alexandra

机构信息

Transplant Center, Presbyterian St. Luke's Medical Center, Denver, Colorado.

Department of Medicine, Presbyterian St. Luke's Medical Center, Denver, Colorado.

出版信息

Gastro Hep Adv. 2024 Feb 28;3(4):471-473. doi: 10.1016/j.gastha.2024.02.004. eCollection 2024.

Abstract

Ketamine-induced sclerosing cholangitis has been described with chronic intranasal and intravenous use. Our case follows chronic topical use for peripheral neuropathy. It is also uniquely associated with early inflammatory bowel disease, a known complication of primary sclerosing cholangitis.

摘要

氯胺酮诱导的硬化性胆管炎已在慢性鼻内和静脉使用时被描述过。我们的病例是在慢性局部使用氯胺酮治疗周围神经病变后出现的。它还与早期炎症性肠病有独特关联,而炎症性肠病是原发性硬化性胆管炎的一种已知并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/447c/11308429/320c9561cb93/gr1.jpg

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