Adelsheimer Andrew, Wang Joseph, Lu Daniel Y, Elbaum Lindsay, Krishnan Udhay, Cheung Jim W, Feldman Dmitriy N, Wong S Chiu, Horn Evelyn M, Sobol Irina, Goyal Parag, Karas Maria G, Kim Luke K
Division of General Internal Medicine, Department of Medicine, Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York, New York.
Division of Cardiology, Department of Medicine, Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York, New York.
J Soc Cardiovasc Angiogr Interv. 2022 Apr 11;1(2):100027. doi: 10.1016/j.jscai.2022.100027. eCollection 2022 Mar-Apr.
This study evaluates the impact of socioeconomic status (SES) on utilization of mechanical circulatory support (MCS) devices and outcomes in cardiogenic shock (CS).
CS is associated with significant mortality. There is increasing use of temporary MCS devices in CS, and its impact on outcomes is currently under investigation. There is a lack of data on the effect of SES on the utilization of MCS devices in CS.
CS hospitalizations were obtained from the State Inpatient Databases in 2016 from 9 states representing various regions in the United States. The study had exempt institutional review board status as the database includes deidentified data. Hospitalizations were separated into SES cohorts based on the median household income of the patient residence zip code. Utilization of MCS devices and revascularization procedures along with clinical outcomes with CS were compared across the quartiles.
There were 38,520 hospitalizations identified with CS, 42.6% of which were secondary to acute myocardial infarction. Patients from higher SES areas were significantly older but had lower burden of comorbidities. Utilization of temporary MCS devices was higher for hospitalizations from higher SES regions (frequency from the lowest SES quartile to the highest SES quartile: 21.3%, 21.5%, 23.5, and 24.1%, < .01), though revascularization rates were similar. However, there was no significant difference in overall mortality from CS among the 4 quartiles. Patients from regions of higher SES experienced increased hospital costs.
Higher SES regions had increased use of temporary MCS. There was no difference in mortality between SES cohorts.
本研究评估社会经济地位(SES)对机械循环支持(MCS)设备使用情况及心源性休克(CS)结局的影响。
CS与显著的死亡率相关。CS中临时MCS设备的使用日益增加,其对结局的影响目前正在研究中。关于SES对CS中MCS设备使用影响的数据尚缺乏。
从代表美国不同地区的9个州的2016年州住院数据库中获取CS住院病例。由于数据库包含去识别化数据,该研究获得了机构审查委员会的豁免。根据患者居住邮政编码的家庭收入中位数将住院病例分为SES队列。比较四分位数间MCS设备和血运重建手术的使用情况以及CS的临床结局。
共识别出38,520例CS住院病例,其中42.6%继发于急性心肌梗死。来自较高SES地区的患者年龄显著更大,但合并症负担较低。较高SES地区住院病例中临时MCS设备的使用率更高(从最低SES四分位数到最高SES四分位数的频率分别为:21.3%、21.5%、23.5%和24.1%,P<0.01),尽管血运重建率相似。然而,4个四分位数间CS的总体死亡率无显著差异。来自较高SES地区的患者住院费用增加。
较高SES地区临时MCS的使用增加。SES队列之间的死亡率无差异。