Department of Diagnostic Radiology, College of Applied Medical Sciences (Building 115), Taibah University, Prince Naif Rd, Madinah, 42353, Saudi Arabia.
BMC Med Imaging. 2024 Aug 12;24(1):209. doi: 10.1186/s12880-024-01397-z.
Calculating size-specific dose estimates (SSDEs) requires measurement of the patient's anteroposterior (AP) and lateral thickness based on computed tomography (CT) images. However, these measurements can be subject to variation due to inter-observer and intra-observer differences. This study aimed to investigate the impact of these variations on the accuracy of the calculated SSDE.
Four radiographers with 1-10 years of experience were invited to measure the AP and lateral thickness on 30 chest, abdomen, and pelvic CT images. The images were sourced from an internet-based database and anonymized for analysis. The observers were trained to perform the measurements using MicroDicom software and asked to repeat the measurements 1 week later. The study was approved by the institutional review board at Taibah University, and written informed consent was obtained from the observers. Statistical analyses were performed using Python libraries Pingouin (version 0.5.3), Seaborn (version 0.12.2), and Matplotlib (version 3.7.1).
The study revealed excellent inter-observer agreement for the calculated effective diameter and AP thickness measurements, with Intraclass correlation coefficients (ICC) values of 0.95 and 0.96, respectively. The agreement for lateral thickness measurements was lower, with an ICC value of 0.89. The second round of measurements yielded nearly the same levels of inter-observer agreement, with ICC values of 0.97 for the effective diameter, 1.0 for AP thickness, and 0.88 for lateral thickness. When the consistency of the observer was examined, excellent consistency was found for the calculated effective diameter, with ICC values ranging from 0.91 to 1.0 for all observers. This was observed despite the lower consistency in the lateral thickness measurements, which had ICC values ranging from 0.78 to 1.0.
The study's findings suggest that the measurements required for calculating SSDEs are robust to inter-observer and intra-observer differences. This is important for the clinical use of SSDEs to set diagnostic reference levels for CT scans.
计算基于体素的剂量估算(SSDE)需要根据计算机断层扫描(CT)图像测量患者的前后径(AP)和侧厚。然而,这些测量可能因观察者间和观察者内的差异而存在差异。本研究旨在探讨这些变化对计算 SSDE 准确性的影响。
邀请了 4 名具有 1-10 年经验的放射技师对 30 例胸部、腹部和盆腔 CT 图像进行 AP 和侧厚测量。这些图像来自一个基于互联网的数据库,并经过匿名化分析。观察者使用 MicroDicom 软件进行测量培训,并要求在 1 周后重复测量。该研究得到了塔巴大学机构审查委员会的批准,并获得了观察者的书面知情同意。使用 Python 库 Pingouin(版本 0.5.3)、Seaborn(版本 0.12.2)和 Matplotlib(版本 3.7.1)进行统计分析。
研究显示,计算有效直径和 AP 厚度测量的观察者间一致性非常好,内类相关系数(ICC)值分别为 0.95 和 0.96。侧厚测量的一致性较低,ICC 值为 0.89。第二轮测量的观察者间一致性几乎相同,ICC 值分别为有效直径 0.97、AP 厚度 1.0 和侧厚 0.88。当检查观察者的一致性时,发现计算有效直径的一致性非常好,所有观察者的 ICC 值范围为 0.91 至 1.0。尽管侧厚测量的一致性较低,ICC 值范围为 0.78 至 1.0,但仍观察到这种情况。
研究结果表明,计算 SSDE 所需的测量值对观察者间和观察者内的差异具有稳健性。这对于使用 SSDE 为 CT 扫描设置诊断参考水平的临床应用非常重要。