From the Department of Anesthesiology and Pain Medicine, Inselspital, University Hospital, University of Bern, Bern, Switzerland.
Institute for Medical Education, University of Bern, Bern, Switzerland.
A A Pract. 2024 Aug 13;18(8):e01831. doi: 10.1213/XAA.0000000000001831. eCollection 2024 Aug 1.
In Switzerland, approximately 32,000 patients are hospitalized annually due to adverse drug reactions (ADRs), representing 2.3% of all hospitalizations. During the perioperative period, the administration of a variety of drugs from different classes over a relatively short period of time increases the risk of ADR. Here, we describe the case of a 32-year-old woman who was administered droperidol to treat nausea in the recovery room after a myomectomy and who subsequently became comatose. Correctable metabolic, respiratory, and cerebrovascular disorders were ruled out. Six hours after the event, she was extubated without residual effects. We discuss potential ADR for droperidol.
在瑞士，每年约有 32000 名患者因药物不良反应（ADR）住院，占住院总人数的 2.3%。在围手术期，由于在相对较短的时间内使用了多种不同类别的药物，因此增加了发生 ADR 的风险。在这里，我们描述了一例 32 岁女性的病例，她在子宫肌瘤切除术后在恢复室中接受了氟哌利多治疗恶心，随后昏迷。可纠正的代谢、呼吸和脑血管疾病已被排除。事件发生后 6 小时，她拔管后无残留影响。我们讨论了氟哌利多的潜在 ADR。
