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原发性肠道尤因肉瘤:病例报告及文献综述

Primary Ewing's sarcoma of the intestine: case report and literature review.

作者信息

Luo Baofa, Gao Wei, Li Ting, Yu Xinran, Guo Fei

机构信息

Department of Medical Imaging, People's Hospital of Wenshan Prefecture, Wenshan, Yunnan, China.

Department of Medical Imaging, The First People's Hospital of Honghe State, Honghe, Yunnan, China.

出版信息

Front Oncol. 2024 Jul 30;14:1357945. doi: 10.3389/fonc.2024.1357945. eCollection 2024.

DOI:10.3389/fonc.2024.1357945
PMID:39139288
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11319815/
Abstract

Ewing sarcoma (ES)/peripheral primitive neuroectodermal tumor is a highly aggressive malignant tumor that typically presents in bone and soft tissue. Primary ES of the intestine is relatively rare, which poses a challenge in distinguishing it from other primary tumors of the small intestine through imaging. This article details a case study of ES originating in the intestine. Computed tomography (CT) imaging suggested a small intestinal stromal tumor, and so the patient underwent resection of the small bowel and omental tumor. Pathology results confirmed the diagnosis of ES of the small intestine. Following surgery, the patient underwent six cycles of chemotherapy, and a follow-up positron emission tomography-CT revealed widespread dissemination of the disease with intraperitoneal metastasis, ultimately resulting in the death of the patient.

摘要

尤因肉瘤(ES)/外周原始神经外胚层肿瘤是一种侵袭性很强的恶性肿瘤,通常发生于骨骼和软组织。原发性肠道ES相对罕见,通过影像学将其与其他小肠原发性肿瘤区分开来具有挑战性。本文详细介绍了一例起源于肠道的ES病例研究。计算机断层扫描(CT)成像提示为小肠间质瘤,因此患者接受了小肠和网膜肿瘤切除术。病理结果证实为小肠ES。手术后,患者接受了六个周期的化疗,随访正电子发射断层扫描-CT显示疾病广泛播散并伴有腹膜转移,最终导致患者死亡。

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本文引用的文献

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Rare presentation in a rare case of pancreatic extraosseous Ewing's sarcoma: A case report.罕见病例报告:胰腺骨外尤文肉瘤的罕见表现。
Medicine (Baltimore). 2022 Nov 25;101(47):e31752. doi: 10.1097/MD.0000000000031752.
2
Ewing sarcoma of the ileum with wide multiorgan metastases: A case report and review of literature.回肠尤因肉瘤伴多器官广泛转移:一例报告并文献复习
World J Gastrointest Oncol. 2022 Aug 15;14(8):1585-1593. doi: 10.4251/wjgo.v14.i8.1585.
3
Malignant gastrointestinal neuroectodermal tumor presenting with small intestinal obstruction: A case report.
以小肠梗阻为表现的恶性胃肠道神经外胚层肿瘤:病例报告
DEN Open. 2022 Apr 10;2(1):e119. doi: 10.1002/deo2.119. eCollection 2022 Apr.
4
Challenges of Diagnosing Primary Ewing's Sarcoma in the Small Intestine of the Elderly: A Case Report.老年小肠原发性尤因肉瘤诊断面临的挑战:一例报告
Front Oncol. 2021 Jul 9;11:565196. doi: 10.3389/fonc.2021.565196. eCollection 2021.
5
Ewing sarcoma of the jejunum: A case report and literature review.空肠尤因肉瘤:一例报告及文献综述
World J Gastrointest Surg. 2021 May 27;13(5):507-515. doi: 10.4240/wjgs.v13.i5.507.
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Frequency of Translocation t(11;22)(q24;q12) Using Fluorescence In Situ Hybridization (FISH) in Histologically and Immunohistochemically Diagnosed Cases of Ewing's Sarcoma.采用荧光原位杂交(FISH)技术检测组织学和免疫组织化学诊断的尤因肉瘤病例中11号与22号染色体易位t(11;22)(q24;q12)的频率
Cureus. 2020 Aug 20;12(8):e9885. doi: 10.7759/cureus.9885.
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Primary Ewing's sarcoma in a small intestine - a case report and review of the literature.小肠原发性尤因肉瘤——一例报告并文献复习
BMC Surg. 2020 May 25;20(1):113. doi: 10.1186/s12893-020-00774-z.
8
Extraskeletal Ewing's sarcoma/peripheral primitive neuroectodermal tumor of the small bowel presenting with gastrointestinal perforation.发生胃肠道穿孔的小肠骨外尤文肉瘤/外周原始神经外胚层肿瘤
Clin Exp Gastroenterol. 2019 Jun 25;12:279-285. doi: 10.2147/CEG.S203697. eCollection 2019.
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Extraskeletal Ewing Sarcoma of the Jejunum: A Case Report.空肠骨外尤文肉瘤:一例报告
Perm J. 2019;23. doi: 10.7812/TPP/18-255. Epub 2019 Jun 7.
10
A mesenteric primary peripheral Ewing's sarcoma/primitive neuroectodermal tumor with molecular cytogenetic analysis: Report of a rare case and review of literature.一例经分子细胞遗传学分析的肠系膜原发性外周型尤因肉瘤/原始神经外胚层肿瘤:罕见病例报告及文献复习
Indian J Pathol Microbiol. 2018 Apr-Jun;61(2):248-251. doi: 10.4103/IJPM.IJPM_546_17.