Kaur Avneet, Waghmare Pramod W, Dodwad Vidya, Patil Vishakha, Mukul Mansi, Husain Rashida
Periodontology, Bharati Vidyapeeth (Deemed to be University) Dental College and Hospital, Pune, IND.
Cureus. 2024 Jul 14;16(7):e64510. doi: 10.7759/cureus.64510. eCollection 2024 Jul.
This study aimed to assess the efficacy of hyaluronic acid (HA) gel injections in deficient papillae and record the effects for four weeks.
Fifteen deficient class 1 papilla sites according to Nordland and Tarnow classification were included. After scaling and root planing, 0.5 ml HA gel was injected into the papillae. Measurements of black triangle height (BTH) and black triangle area (BTA) from the contact point to the most coronal level of the visible papilla tip were done on the clinical photographs using ImageJ software at baseline, one week, and four weeks postoperatively, and a comparison was made. Descriptive data were examined using the mean and standard deviation (SD). Paired t-test was used for intragroup comparisons, with p-values <0.05 considered significant. All the data analysis was done using SPSS software version 25.0.
There was a mean decrease in the BTA from baseline (0.54 mm), one week (0.13 mm), to four weeks (0.26 mm) with a slight loss of papilla volume from the first week to the fourthweek, and this decrease in area was statistically significant. A mean decrease in the BTH throughout the follow-ups from baseline (1.36 mm) to the first week (0.30 mm) to the fourth week (0.73) was recorded with a slight loss of papilla volume from the first week to the fourthweek, and this decrease in height was also statistically significant (p < 0.05). However, the decrease in the BTA and BTH recorded was more from baseline to the first week as compared to baseline to the fourth week postoperatively.
HA gel is an effective treatment for minimally invasive papilla augmentation, particularly in class I Nordland and Tarnow papilla deficits.
本研究旨在评估透明质酸（HA）凝胶注射治疗缺如乳头的疗效，并记录四周内的效果。
纳入15个根据诺德兰和塔诺分类法判定为1类缺如乳头部位。在进行龈上洁治和根面平整后，向乳头内注射0.5 ml HA凝胶。使用ImageJ软件在基线、术后1周和4周时，对临床照片上从接触点到可见乳头尖端最冠方水平的黑三角高度（BTH）和黑三角面积（BTA）进行测量，并进行比较。描述性数据采用均值和标准差（SD）进行分析。组内比较采用配对t检验，p值<0.05认为具有统计学意义。所有数据分析均使用SPSS 25.0软件完成。
BTA从基线时的平均0.54 mm、1周时的0.13 mm降至4周时的0.26 mm，从第1周开始到第4周乳头体积略有减小，面积减小具有统计学意义。整个随访期间，BTH从基线时的平均1.36 mm降至第1周时的0.30 mm，再降至第4周时的0.73，从第1周开始到第4周乳头体积略有减小，高度降低也具有统计学意义（p<0.05）。然而，与术后基线至第4周相比，BTA和BTH从基线至第1周的下降幅度更大。
HA凝胶是微创乳头增大的有效治疗方法，尤其适用于诺德兰和塔诺I类乳头缺损。
