Andrade Carolina Horta, Nonato Maria Cristina, da Silva Emery Flavio
Center for Research and Advancement in Fragments and Molecular Targets (CRAFT), School of Pharmaceutical Sciences at Ribeirao Preto, University of São Paulo, Ribeirão Preto, São Paulo 05508-060, Brazil.
Laboratory for Molecular Modeling and Drug Design (LabMol), Faculty of Pharmacy, Universidade Federal de Goiás, Goiânia, Goiás 74605-170, Brazil.
ACS Med Chem Lett. 2024 Jul 23;15(8):1174-1177. doi: 10.1021/acsmedchemlett.4c00296. eCollection 2024 Aug 8.
We introduce the Center for Research and Advancement in Fragments and Molecular Targets (CRAFT), a pioneering research center established in 2021 through a collaboration between the University of São Paulo (USP) and the Federal University of Goiás (UFG). CRAFT integrates fragment-based drug discovery (FBDD), artificial intelligence (AI), and structural biology to develop novel therapeutic strategies. We have created fragment and target libraries and utilize AI models to streamline the drug discovery process. We invite the global scientific community to collaborate with us in addressing neglected diseases, with the goal of enhancing research capabilities and fostering scientific innovation across Latin America.
我们介绍碎片与分子靶点研究与推进中心（CRAFT），这是一个于2021年通过圣保罗大学（USP）和戈亚斯联邦大学（UFG）合作建立的开创性研究中心。CRAFT整合基于片段的药物发现（FBDD）、人工智能（AI）和结构生物学，以开发新的治疗策略。我们创建了片段和靶点库，并利用人工智能模型简化药物发现过程。我们邀请全球科学界与我们合作，共同应对被忽视的疾病，目标是提高整个拉丁美洲的研究能力，促进科学创新。
