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原发性高血压的行为治疗与药物治疗——一项必要的比较。

Behavioral versus pharmacological treatments for essential hypertension--a needed comparison.

作者信息

Luborsky L, Crits-Christoph P, Brady J P, Kron R E, Weiss T, Cohen M, Levy L

出版信息

Psychosom Med. 1982 May;44(2):203-13. doi: 10.1097/00006842-198205000-00006.

Abstract

Comparison of mild-to-moderate essential hypertension patients treated for 6 weeks by antihypertensive medication versus metronome-conditioned relaxation versus biofeedback versus a mild exercise control procedure showed that those on medication achieved the greatest decrease in blood pressure. The relaxation and biofeedback groups decreased more than the mild exercise group, as predicted, but not significantly more. The differences in benefits of the groups were not a function of group differences in initial blood pressure levels nor in compliance. Nor did the groups differ in the side effects that are usually associated with medications. A second phase of 6 weeks with another treatment or combination of treatments did not add significantly. Some characteristics of patients moderately predicted treatment benefits, for example, high scores on the Jenkins Activity Survey Scales (1) [Type A, S or H], for the relaxation and biofeedback treated patients predicted which patients received greater benefits.

摘要

对轻度至中度原发性高血压患者进行为期6周的治疗,比较使用抗高血压药物治疗、节拍器调节放松疗法、生物反馈疗法与轻度运动控制程序的效果,结果显示使用药物治疗的患者血压下降幅度最大。如预期的那样,放松疗法组和生物反馈疗法组的血压下降幅度大于轻度运动组,但差异并不显著。各组治疗效果的差异既不是初始血压水平的组间差异所致,也不是依从性的组间差异所致。各组在通常与药物相关的副作用方面也没有差异。进行为期6周的另一项治疗或联合治疗的第二阶段,效果并没有显著增加。患者的一些特征适度地预测了治疗效果,例如,在詹金斯活动量表(1)[A型、S型或H型]上得分较高,对于接受放松疗法和生物反馈疗法治疗的患者来说,这一特征可以预测哪些患者能获得更大的益处。

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