Deolikar Sayali, Jawdekar Ashwin, Saraf Tanvi, Thribhuvanan Lakshmi, Tirupathi Sunnypriyatham
Department of Pedodontics and Preventive Dentistry, Dr DY Patil Dental College and Hospital, Dr DY Patil Vidyapeeth (Deemed to be University), Pune, Maharashtra, India.
Department of Pediatric and Preventive Dentistry, Bharati Vidyapeeth Dental College and Hospital, Bharati Vidyapeeth (Deemed to be University), Mumbai, Maharashtra, India.
Int J Clin Pediatr Dent. 2024 Apr;17(4):461-466. doi: 10.5005/jp-journals-10005-2832.
The study aimed to evaluate and compare the antimicrobial efficacy of (0.5%) mouthwash, (0.5%) mouthwash, and 0.12% chlorhexidine gluconate mouthwash against
A total of 60 samples of the five mouthwash preparations were prepared to check for their antimicrobial efficacy. The zone of inhibition (ZOI) against was measured as a diameter in mm, and the minimum inhibitory concentration (MIC) of mouthwash preparations was measured as μg/mL. All the groups were compared statistically using the Mann-Whitney test and the Kruskal-Wallis test.
The highest ZOI was observed in group V chlorhexidine gluconate [mean: 20.8, standard deviation (SD): 0.58], followed by group III (alcohol-free) (mean: 15.5, SD: 0.67), group IV (alcohol-based) (mean: 14.08, SD: 0.66), and group II (alcohol-based) (mean: 13.2, SD: 0.45). The least ZOI was observed in group I (alcohol-free) (mean: 10.7, SD: 0.45). This difference was statistically significant ( < 0.01). The MIC was similar in all the groups ( = 0.13).
Chlorhexidine gluconate 0.12% mouthwash showed the best antimicrobial action; however, mouthwash showed potential against mouthwash exhibited limited antimicrobial activity.
Deolikar S, Jawdekar A, Saraf T, Comparative Evaluation of the Antimicrobial Efficacy of (0.5%) Mouthwash, (0.5%) Mouthwash, and 0.12% Chlorhexidine Gluconate Mouthwash against An Study. Int J Clin Pediatr Dent 2024;17(4):461-466.
本研究旨在评估并比较(0.5%)漱口水、(0.5%)漱口水和0.12%葡萄糖酸氯己定漱口水对……的抗菌效果。
制备了五种漱口水制剂的60个样本,以检查其抗菌效果。针对……的抑菌圈(ZOI)以毫米为单位测量直径,漱口水制剂的最低抑菌浓度(MIC)以μg/mL为单位测量。所有组均使用曼-惠特尼U检验和克鲁斯卡尔-沃利斯检验进行统计学比较。
在第五组葡萄糖酸氯己定中观察到最高的抑菌圈(均值:20.8,标准差(SD):0.58),其次是第三组(无酒精)(均值:15.5,SD:0.67)、第四组(含酒精)(均值:14.08,SD:0.66)和第二组(含酒精)(均值:13.2,SD:0.45)。在第一组(无酒精)中观察到最小的抑菌圈(均值:10.7,SD:0.45)。这种差异具有统计学意义(P<0.01)。所有组的最低抑菌浓度相似(P = 0.13)。
0.12%葡萄糖酸氯己定漱口水显示出最佳的抗菌作用;然而,……漱口水显示出对……的潜在效果,……漱口水表现出有限的抗菌活性。
Deolikar S, Jawdekar A, Saraf T, (0.5%)漱口水、(0.5%)漱口水和0.12%葡萄糖酸氯己定漱口水对……的抗菌效果比较评估。一项……研究。《国际临床儿科牙科学杂志》2024;17(4):461 - 466。