Shawwaf Kenan A, Aly Mohamed R, Botros Michael M, Moosavi Ryan S, Zeineddine Rawan M, Lackey Jesse J, Sandstrom Beth, Farina Juan M, Jaroszewski Dawn E
Department of Cardiovascular and Thoracic Surgery, Mayo Clinic, Phoenix, AZ, USA.
J Thorac Dis. 2024 Jul 30;16(7):4359-4378. doi: 10.21037/jtd-24-417. Epub 2024 Jul 18.
Revision of a prior failed pectus excavatum (PE) repair is occasionally required. These procedures may be technically more complex and have a greater risk of complications. This study was performed to evaluate the outcomes of adult patients undergoing revision procedures.
A retrospective review of adult patients who underwent revision of a prior PE repair from 2010 to 2023 at Mayo Clinic Arizona was performed. Patients were classified by prior procedure [minimally invasive repair of pectus excavatum (MIRPE), Open/Ravitch, and both] and the type of revision procedure performed [MIRPE, hybrid MIRPE, complex hybrid reconstruction, or complex reconstruction of acquired thoracic dystrophy (ATD)]. Outcomes and complications of these groups were analyzed and compared.
In total, 190 revision cases were included (mean age was 33±10 years; 72.6% males, mean Haller Index: 4.4±1.8). For the initial repair procedure, 90 (47.4%) patients had a previous MIRPE, 87 (45.8%) patients a prior open repair, and thirteen (6.8%) patients had both. Furthermore, 30 (15.8%) patients had two or more prior interventions. Patients having had a prior MIRPE were able to be repaired with a revision MIRPE in 82.2% of the cases. Conversely, patients with a prior open repair (including those who had both prior MIRPE and open repairs) were much more likely to require complex reconstructions (85%) as none of the ATD patients in this group had an attempted MIRPE. Operative times were shortest in the MIRPE redo approach and longest in the complex reconstruction of the ATD patients (MIRPE 3.5±1.3 hours, ATD 6.9±1.8 hours; P<0.001). The median length of hospital stay was 5 days [interquartile range (IQR), 3.0 days] with the shortest being the MIRPE approach and the longest occurring in the complex reconstruction of the ATD patients [MIRPE 4 days (IQR, 3.0 days); ATD 7 days (IQR, 4.0 days); P<0.001]. Major and minor complications were more frequent in the ATD complex reconstruction group. Preoperative chronic pain was present in over half of the patients (52.6%). Although resolution was seen in a significant number of patients, significant pain issues persisted in 8.8% of the patients postoperatively. Overall, persistent, long term chronic pain was greatest in the post open/Ravitch patient group (open 13.6% MIRPE 3.6%, P=0.02).
Revision of a prior failed PE repair can be technically complex with a high risk of complications, prolonged duration of surgery, and lengthy hospitalization. Chronic pain is prevalent and its failure to completely resolve after surgery is not uncommon. The initial failed repair will influence the type of procedure that can be performed and potentially subsequent complications. Even when some recurrences after previous PE surgeries can be repaired with acceptable results, this study demonstrates the importance of proper primary repair due to these increased risks.
偶尔需要对先前失败的漏斗胸(PE)修复进行翻修。这些手术在技术上可能更复杂,并发症风险更高。本研究旨在评估接受翻修手术的成年患者的治疗结果。
对2010年至2023年在亚利桑那州梅奥诊所接受先前PE修复翻修的成年患者进行回顾性研究。患者按先前手术方式[漏斗胸微创修复术(MIRPE)、开放/拉维奇手术,以及两者皆有]和所进行的翻修手术类型[MIRPE、混合MIRPE、复杂混合重建,或后天性胸廓发育不良(ATD)的复杂重建]进行分类。分析并比较这些组别的治疗结果和并发症。
共纳入190例翻修病例(平均年龄33±10岁;72.6%为男性,平均哈勒指数:4.4±1.8)。对于初次修复手术,90例(47.4%)患者先前接受过MIRPE,87例(45.8%)患者先前接受过开放修复,13例(6.8%)患者两者皆有。此外,30例(15.8%)患者接受过两次或更多次先前干预。先前接受过MIRPE的患者中,82.2%的病例能够通过翻修MIRPE进行修复。相反,先前接受过开放修复的患者(包括那些先前既接受过MIRPE又接受过开放修复的患者)更有可能需要复杂重建(85%),因为该组中没有ATD患者尝试进行MIRPE。手术时间在MIRPE再次手术方法中最短,在ATD患者的复杂重建中最长(MIRPE为3.5±1.3小时,ATD为6.9±1.8小时;P<0.001)。住院时间中位数为5天[四分位间距(IQR),3.0天],最短的是MIRPE方法,最长的发生在ATD患者的复杂重建中[MIRPE为4天(IQR,3.0天);ATD为7天(IQR,4.0天);P<0.001]。ATD复杂重建组的主要和次要并发症更常见。超过一半的患者(52.6%)术前存在慢性疼痛。尽管大量患者疼痛得到缓解,但术后仍有8.8%的患者存在明显的疼痛问题。总体而言,开放/拉维奇术后患者组持续的长期慢性疼痛最为严重(开放组为13.6%,MIRPE组为3.6%,P=0.02)。
对先前失败的PE修复进行翻修在技术上可能很复杂,并发症风险高,手术时间长,住院时间长。慢性疼痛很普遍,术后未能完全缓解并不罕见。初次修复失败会影响可进行的手术类型以及潜在的后续并发症。即使先前PE手术后的一些复发可以通过可接受的结果进行修复,但本研究表明由于这些风险增加,正确的初次修复非常重要。