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2010 年、2015 年和 2019 年欧洲因肺癌、乳腺癌和黑色素瘤导致的死亡率的生产力损失。

The productivity cost of mortality due to lung cancer, breast cancer and melanoma in Europe across 2010, 2015 and 2019.

机构信息

MSD, Budapest, Hungary.

Adelphi Values PROVE™, Bollington, UK.

出版信息

J Cancer Policy. 2024 Dec;42:100499. doi: 10.1016/j.jcpo.2024.100499. Epub 2024 Aug 13.

Abstract

BACKGROUND

Cancer caused an estimated 2.2 million deaths across Europe in 2020. This analysis estimated the cost of lost productivity due to premature deaths associated with lung, breast and melanoma cancer and investigated the temporal trends across European regions across 2010, 2015 and 2019.

METHOD

The human capital approach was used to estimate the indirect costs from lung, melanoma, and breast cancers (ICD-10 code: C33-34, C43, and C50, respectively) in Northern, Eastern, Southern, and Western Europe. Age-specific mortality, and country-specific wages and employment rates were used to calculate years of productive life lost (YPLL), YPLL/death and present value of future lost productivity (PVFLP). Data were sourced from the World Health Organization, Eurostat, and the World Bank.

RESULTS

The number of cancer deaths remained relatively stable from 2010 to 2019. YPLL/death decreased across all European regions and for all cancers between 2010 and 2019 (reported ranges across European regions; lung cancer: 25-42 %; breast cancer: 18-21 %; melanoma: 31-37 %). In Europe, the decrease in PVFLP in 2019 compared to 2010 was €2995M for lung cancer, €295M for melanoma, and €466M for breast cancer, with an overall reduction of productivity cost of €3756M in these cancer types.

CONCLUSION

The results from this study illustrate a decreased trend in productivity costs from 2010 to 2019 which could be driven by deaths occurring at an older age, suggesting that advances in cancer prevention and the treatment landscape have extended the life of cancer patients, yielding less productivity losses.

POLICY SUMMARY

The indirect economic costs modelled show the impact of past effective health policies and new treatments. Continued efforts to improve public health policies in supporting public awareness of risk factors and value of early diagnosis could lead to further reduction in these losses. Prevention, early diagnosis, and activation of early treatment pathways could serve to reduce loss of life and improve productivity.

摘要

背景

2020 年,欧洲有 220 万人因癌症死亡。本分析估算了与肺癌、乳腺癌和黑色素瘤相关的过早死亡导致的生产力损失成本,并研究了 2010 年、2015 年和 2019 年期间欧洲各地区的时间趋势。

方法

采用人力资本法估算了北欧、东欧、南欧和西欧的肺癌(ICD-10 编码:C33-34)、黑色素瘤(C43)和乳腺癌(C50)的间接成本。使用特定年龄的死亡率、国家特定的工资和就业率来计算生产性生命损失年数(YPLL)、YPLL/死亡和未来丧失生产力的现值(PVFLP)。数据来源于世界卫生组织、欧盟统计局和世界银行。

结果

2010 年至 2019 年期间,癌症死亡人数相对稳定。2010 年至 2019 年期间,所有欧洲地区和所有癌症的 YPLL/死亡人数均呈下降趋势(欧洲各地区报告范围;肺癌:25-42%;乳腺癌:18-21%;黑色素瘤:31-37%)。在欧洲,与 2010 年相比,2019 年肺癌、黑色素瘤和乳腺癌的 PVFLP 分别减少了 2995 万欧元、295 万欧元和 466 万欧元,这些癌症类型的生产力成本总体减少了 3756 万欧元。

结论

本研究结果表明,2010 年至 2019 年生产力成本呈下降趋势,这可能是由于死亡年龄较大所致,这表明癌症预防和治疗领域的进展延长了癌症患者的生命,减少了生产力损失。

政策要点

模型化的间接经济成本显示了过去有效卫生政策和新治疗方法的影响。继续努力改善公共卫生政策,提高公众对风险因素和早期诊断价值的认识,可能会进一步减少这些损失。预防、早期诊断和激活早期治疗途径可能有助于减少生命损失和提高生产力。

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