[Unusual abdominal apudomas. II. Immunohistochemical detection of glucagon in a primary apudoma of the liver].

An autopsy confirmed, primary malignant APUDoma of the liver is described. Immunohistochemical methods demonstrated the presence of glucagon in some 20% of tumor cells. Clinically the 66 year old patient had presented with an abortive form of the glucagonoma syndrome with diabetes mellitus, anemia and profound weight loss.