Villarreal Cameron X, Shen Xin, Alhulail Ahmad A, Buffo Nicholas M, Zhou Xiaopeng, Pogue Evan, Özen Ali Caglar, Chiew Mark, Sawiak Stephen, Emir Uzay, Chan Deva D
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, 47907, USA.
Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, 94158, USA.
Skeletal Radiol. 2025 Mar;54(3):601-610. doi: 10.1007/s00256-024-04774-5. Epub 2024 Aug 17.
In this work, we evaluate the sodium magnetic resonance imaging (MRI) capabilities of a three-dimensional (3D) dual-echo ultrashort echo time (UTE) sequence with a novel rosette petal trajectory (PETALUTE), in comparison to the 3D density-adapted (DA) radial spokes UTE sequence in human articular cartilage in the knee.
We scanned five healthy subjects using a 3D dual-echo PETALUTE acquisition and two comparable implementations of 3D DA-radial spokes acquisitions, one matching the number of k-space projections (Radial - Matched Spokes) and the other matching the total number of samples (Radial - Matched Samples) acquired in k-space.
The PETALUTE acquisition enabled equivalent sodium quantification in articular cartilage volumes of interest (168.8 ± 29.9 mM, mean ± standard deviation) to those derived from the 3D radial acquisitions (171.62 ± 28.7 mM and 149.8 ± 22.2 mM, respectively). We achieved a 41% shorter scan time of 2:06 for 3D PETALUTE, compared to 3:36 for 3D radial acquisitions. We also evaluated the feasibility of further acceleration of the PETALUTE sequence through retrospective compressed sensing with 2 × and 4 × acceleration of the first echo and showed structural similarity of 0.89 ± 0.03 and 0.87 ± 0.03 when compared to non-retrospectively accelerated reconstruction.
We demonstrate improved scan time with equivalent performance using a 3D dual-echo PETALUTE sequence compared to the 3D DA-radial sequence for sodium MRI of articular cartilage.
在本研究中，我们评估了一种具有新型玫瑰花结花瓣轨迹（PETALUTE）的三维（3D）双回波超短回波时间（UTE）序列的钠磁共振成像（MRI）能力，并与用于膝关节人类关节软骨的3D密度自适应（DA）径向辐条UTE序列进行比较。
我们对五名健康受试者进行了扫描，采用3D双回波PETALUTE采集以及两种类似的3D DA径向辐条采集方法，一种是匹配k空间投影数量（径向 - 匹配辐条），另一种是匹配在k空间中采集的样本总数（径向 - 匹配样本）。
PETALUTE采集在感兴趣的关节软骨体积中实现了与3D径向采集（分别为171.62±28.7 mM和149.8±22.2 mM）相当的钠定量（168.8±29.9 mM，平均值±标准差）。与3D径向采集的3:36相比，3D PETALUTE的扫描时间缩短了41%，为2:06。我们还评估了通过对第一次回波进行2倍和4倍加速的回顾性压缩感知进一步加速PETALUTE序列的可行性，与非回顾性加速重建相比，结构相似性分别为0.89±0.03和0.87±0.03。
我们证明，与用于关节软骨钠MRI的3D DA径向序列相比，使用3D双回波PETALUTE序列在扫描时间缩短的情况下具有同等性能。
