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机器人辅助与传统颈清扫术:一项关于围手术期和肿瘤学结果的倾向评分匹配病例对照研究。

Robot-assisted versus conventional neck dissection: a propensity score matched case-control study on perioperative and oncologic outcomes.

机构信息

Department of Oral & Maxillofacial Surgery, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Oral Science Research Center, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

出版信息

J Robot Surg. 2024 Aug 17;18(1):323. doi: 10.1007/s11701-024-02079-2.

Abstract

The widespread acceptance of robotic surgery is extending to oral procedures. The demand for minimally invasive techniques is driving research into the cosmetic and oncologic benefits of robotic neck surgery. This study used propensity score matching to analyze the clinical course and postoperative outcomes of robot-assisted neck dissections for oncologic efficacy and surgical safety. Between May 2020 and April 2024, 200 OSCC patients underwent surgery and 42 were excluded. The cohort included 158 patients, 128 of whom underwent unilateral neck dissection and 30 of whom underwent bilateral neck dissection. Robotic-assisted neck dissection (RAND) was performed in 36 patients while conventional transcervical neck dissection (CTND) was performed in 122 patients. Data analysis included several factors, including lymph node retrieval and perioperative outcomes, with 1:1 propensity score matching to ensure fairness. Each of the 39 neck specimens with 36 patients was selected. The CTND group was 8 years older overall than the RAND group, but otherwise similar in terms of primary site and clinical stage. The RAND group had a 55-min longer operative time and 140 cc more hemovac drainage than the CTND group, but the hospital stay and intensive care unit duration were the same, and the number of lymph nodes retrieved was the same. Survival rates also showed no difference across all stages. This shows that RAND is in no way inferior to CTND in terms of perioperative or oncologic outcomes, and demonstrates the safety of robot-assisted surgery, even in patients who require flaps or in patients with advanced stages.

摘要

机器人手术的广泛应用正在扩展到口腔手术。微创技术的需求推动了对机器人颈部手术美容和肿瘤效益的研究。本研究使用倾向评分匹配分析了机器人辅助颈部解剖术的临床过程和术后结果,以评估其在肿瘤疗效和手术安全性方面的作用。在 2020 年 5 月至 2024 年 4 月期间,有 200 例 OSCC 患者接受了手术,其中 42 例被排除在外。该队列包括 158 例患者,其中 128 例行单侧颈部解剖术,30 例行双侧颈部解剖术。36 例患者接受了机器人辅助颈部解剖术(RAND),122 例患者接受了传统经颈颈部解剖术(CTND)。数据分析包括淋巴结检出和围手术期结果等多个因素,并进行了 1:1 的倾向评分匹配以确保公平性。每个患者选择 36 例患者的 39 个颈部标本。CTND 组的平均年龄比 RAND 组大 8 岁,但原发部位和临床分期相似。RAND 组的手术时间比 CTND 组长 55 分钟,引流血量多 140cc,但住院时间和重症监护病房时间相同,淋巴结检出数量也相同。各期生存率也无差异。这表明 RAND 在围手术期或肿瘤学结果方面并不逊于 CTND,并证明了机器人辅助手术的安全性,即使在需要皮瓣的患者或晚期患者中也是如此。

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