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是否午睡?一项基于习惯性日间午睡与健康结局的队列研究的荟萃分析证据。

To nap or not? Evidence from a meta-analysis of cohort studies of habitual daytime napping and health outcomes.

机构信息

The First Affiliated Hospital of Xinxiang Medical University, Henan, China.

Peking University Sixth Hospital, Peking University Institute of Mental Health, NHC Key Laboratory of Mental Health (Peking University), National Clinical Research Center for Mental Disorders (Peking University Sixth Hospital), Peking University, Beijing, China; Peking-Tsinghua Centre for Life Sciences and PKU-IDG/McGovern Institute for Brain Research, Peking University, Beijing, China.

出版信息

Sleep Med Rev. 2024 Dec;78:101989. doi: 10.1016/j.smrv.2024.101989. Epub 2024 Aug 8.

DOI:10.1016/j.smrv.2024.101989
PMID:39153335
Abstract

Habitual daytime napping is a common behavioral and lifestyle practice in particular countries and is often considered part of a normal daily routine. However, recent evidence suggests that the health effects of habitual daytime napping are controversial. We systematically searched PubMed, Web of Science, Embase, and Cochrane Library databases from inception to March 9, 2024, to synthesize cohort studies of napping and health outcome risk. A total of 44 cohort studies with 1,864,274 subjects aged 20-86 years (mean age 56.4 years) were included. Overall, habitual napping increased the risk of several adverse health outcomes, including all-cause mortality, cardiovascular disease, metabolic disease, and cancer, and decreased the risk of cognitive impairment and sarcopenia. Individuals with a napping duration of 30 min or longer exhibited a higher risk of all-cause mortality, cardiovascular disease, and metabolic disease, whereas those with napping durations less than 30 min had no significant risks. No significant differences in napping and health risks were observed for napping frequency, percentage of nappers, sample size, sex, age, body mass index, follow-up years, or comorbidity status. These findings indicate that individuals with a long napping duration should consider shortening their daily nap duration to 30 min or less.

摘要

习惯性日间小睡是某些国家常见的行为和生活方式习惯,通常被认为是正常日常活动的一部分。然而,最近的证据表明,习惯性日间小睡对健康的影响存在争议。我们系统地检索了 PubMed、Web of Science、Embase 和 Cochrane Library 数据库,检索时间从建库至 2024 年 3 月 9 日,以综合日间小睡与健康结局风险的队列研究。共纳入了 44 项队列研究,包含 1864274 名年龄在 20-86 岁(平均年龄 56.4 岁)的研究对象。总体而言,习惯性小睡增加了多种不良健康结局的风险,包括全因死亡率、心血管疾病、代谢疾病和癌症,降低了认知障碍和肌肉减少症的风险。小睡时长为 30 分钟或更长的个体发生全因死亡率、心血管疾病和代谢疾病的风险更高,而小睡时长小于 30 分钟的个体则没有显著的风险。在小睡频率、小睡者比例、样本量、性别、年龄、体重指数、随访年限或合并症状态方面,小睡与健康风险之间没有显著差异。这些发现表明,小睡时间较长的个体应考虑将其每日小睡时长缩短至 30 分钟或更短。

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