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老年营养风险指数与接受心脏手术的个体的不良住院结局相关。

The geriatric nutritional risk index is related to adverse hospitalization outcomes in individuals undergoing cardiac surgery.

机构信息

School of Nursing, Fujian Medical University, Fuzhou, Fujian, China.

Department of Nursing, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.

出版信息

Sci Rep. 2024 Aug 18;14(1):19126. doi: 10.1038/s41598-024-69668-x.

DOI:10.1038/s41598-024-69668-x
PMID:39155300
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11330975/
Abstract

Malnutrition is linked to adverse outcomes in post-cardiac surgery patients. This study investigates the correlation between the Geriatric Nutritional Risk Index (GNRI) and adverse hospital outcomes in patients following cardiac surgery. This retrospective study included elderly patients with heart disease who were admitted to the Department of Cardiology, Fujian Medical University Union Hospital from January 2020 to December 2022. Patients were divided into two groups based on the cut-off value (98 g/dL). Data from 407 patients were assessed, with 278 (68.3%) classified as having nutritional risk and 129 (31.7%) as having no nutritional risk. Notable distinctions were observed in body weight, BMI, and left ventricular ejection fraction (P < 0.05). Laboratory indicators indicated lower levels of serum albumin, lymphocytes, red blood cells, hemoglobin, admission blood glucose, and admission triglyceride in the nutritional risk group (P < 0.05). Neutrophils and serum creatinine were higher in the nutritional risk group (P < 0.05). Poor prognosis was prevalent in the nutrition risk group (64.7%), with higher incidences of adverse outcomes (P < 0.05). Univariate and multivariate studies showed that GNRI < 98 g/dL was an independent predictor of postoperative cardiac surgery. Nutritional risk was an important predictor of adverse hospital outcomes after the surgery.

摘要

营养不良与心脏手术后患者的不良结局有关。本研究旨在探讨老年营养风险指数(GNRI)与心脏手术后患者不良医院结局之间的相关性。这项回顾性研究纳入了 2020 年 1 月至 2022 年 12 月期间在福建医科大学附属协和医院心内科住院的老年心脏病患者。根据截断值(98g/dL)将患者分为两组。评估了 407 名患者的数据,其中 278 名(68.3%)存在营养风险,129 名(31.7%)不存在营养风险。两组间体重、BMI 和左心室射血分数存在显著差异(P<0.05)。实验室指标显示营养风险组血清白蛋白、淋巴细胞、红细胞、血红蛋白、入院血糖和入院甘油三酯水平较低(P<0.05)。营养风险组中性粒细胞和血清肌酐较高(P<0.05)。营养风险组预后不良发生率较高(64.7%),不良结局发生率较高(P<0.05)。单因素和多因素研究表明,GNRI<98g/dL 是术后心脏手术的独立预测因子。营养风险是术后不良医院结局的重要预测因子。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a040/11330975/1c6e3d6e4784/41598_2024_69668_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a040/11330975/b7e73010cfd6/41598_2024_69668_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a040/11330975/1c6e3d6e4784/41598_2024_69668_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a040/11330975/b7e73010cfd6/41598_2024_69668_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a040/11330975/1c6e3d6e4784/41598_2024_69668_Fig2_HTML.jpg

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