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龙葵的主要化学成分及抗肿瘤作用机制

Main chemical constituents and mechanism of anti-tumor action of Solanum nigrum L.

机构信息

Department of Pharmacy, Shanghai Municipal Hospital of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

Experiment Center for Science and Technology, Shanghai University of Traditional Chinese Medicine, Shanghai, China.

出版信息

Cancer Med. 2024 Aug;13(16):e7314. doi: 10.1002/cam4.7314.

DOI:10.1002/cam4.7314
PMID:39155844
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11331249/
Abstract

OBJECTIVE

Solanum nigrum L. (SNL) is a natural drugwith diverse bioactive components and multi-targeted anti-tumor effects, gaining increasing attention in clinical application.

METHOD AND RESULTS

This paper reviews the studies on SNL by searching academic databases (Google Scholar, PubMed, Science Direct,and Web of Science, among others), analyzing its chemical compositions (alkaloids, saponins, polysaccharides, and polyphenols, among others), andbriefly describes the anti-tumor mechanisms of the main components.

DISCUSSION

This paper discusses the shortcomings of the current research on SNL and proposes corresponding solutions, providing theoretical support for further research on its biological functions and clinical efficacy.

摘要

目的

龙葵（Solanum nigrum L.）是一种天然药物，具有多种生物活性成分和多靶点抗肿瘤作用，在临床应用中受到越来越多的关注。

方法与结果

本文通过检索学术数据库（Google Scholar、PubMed、Science Direct 和 Web of Science 等），分析其化学成分（生物碱、皂苷、多糖和多酚等），综述了龙葵的研究进展，并简要描述了主要成分的抗肿瘤机制。

讨论

本文讨论了当前龙葵研究的不足之处，并提出了相应的解决方案，为进一步研究其生物学功能和临床疗效提供了理论支持。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/0e38bf3455fc/CAM4-13-e7314-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/6f8f64bbf111/CAM4-13-e7314-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/fa33b90760fb/CAM4-13-e7314-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/aee0b392f41d/CAM4-13-e7314-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/2ce9c19d01b6/CAM4-13-e7314-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/0e38bf3455fc/CAM4-13-e7314-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/6f8f64bbf111/CAM4-13-e7314-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/fa33b90760fb/CAM4-13-e7314-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/aee0b392f41d/CAM4-13-e7314-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/2ce9c19d01b6/CAM4-13-e7314-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/671a/11331249/0e38bf3455fc/CAM4-13-e7314-g006.jpg

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