Vasilopoulou Anthi, Spaho Marina, Theotokis Paschalis, Grekou Alexandra, Meditskou Soultana, Manthou Maria Eleni
Laboratory of Histology and Embryology, Medical School, Faculty of Health Sciences, Aristotle University of Thessaloniki, Greece.
Laboratory of Experimental Neurology and Neuroimmunology, Second Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece.
Med Mycol Case Rep. 2024 Jul 23;45:100662. doi: 10.1016/j.mmcr.2024.100662. eCollection 2024 Sep.
Disseminated histoplasmosis is the form of a mycosis caused by the fungus that mainly occurs in immunosuppressed hosts, usually with non-specific symptoms. In non-endemic areas, where the disease is rarely involved in the differential diagnosis, a delay in treatment may lead to severe medical complications. Due to the rising prevalence of disseminated histoplasmosis in these areas, a thorough medical history is regarded as the decisive factor in prompt diagnosis of the disease. We, herein, report the case of an immunocompetent Greek farmer with disseminated histoplasmosis whose condition was initially misdiagnosed, and the consequential inadequate treatment led to his death.
播散性组织胞浆菌病是由该真菌引起的一种真菌病，主要发生在免疫抑制宿主中，通常表现为非特异性症状。在非流行地区，该病很少参与鉴别诊断，治疗延迟可能导致严重的医学并发症。由于这些地区播散性组织胞浆菌病的患病率不断上升，详细的病史被视为及时诊断该病的决定性因素。在此，我们报告一例免疫功能正常的希腊农民患播散性组织胞浆菌病的病例，其病情最初被误诊，随后治疗不当导致死亡。
