Bellahyane Imane, Moukhlissi Mohamed, Bouabid Meriem, Berhili Soufiane, Mezouar Loubna
Radiation Oncology, Faculty of Medicine and Pharmacy, Mohammed First University Mohammed, Oujda, MAR.
Cureus. 2024 Jul 17;16(7):e64707. doi: 10.7759/cureus.64707. eCollection 2024 Jul.
The Sister Mary Joseph syndrome is characterized by cutaneous metastases localized at the umbilical level. It is a rare clinical sign estimated to occur in 1%-3% of patients with abdominopelvic cancer. The most common histology is adenocarcinoma (75% of cases). The presence of this nodule is often indicative of a poor prognosis, with average survival estimated at two to 11 months without treatment. We report the clinical case of Sister Mary Joseph syndrome in a 50-year-old woman who had been followed for three years for endometrioid adenocarcinoma of the endometrium. The diagnosis was established via umbilical biopsy after a computed tomography scan revealed the presence of an umbilical nodule. The patient is currently undergoing a palliative chemotherapy regimen.
玛丽·约瑟夫修女综合征的特征是皮肤转移灶位于脐部水平。这是一种罕见的临床体征，估计在1% - 3%的腹盆腔癌症患者中出现。最常见的组织学类型是腺癌（占病例的75%）。这个结节的出现通常预示着预后不良，未经治疗的平均生存期估计为2至11个月。我们报告了一名50岁女性的玛丽·约瑟夫修女综合征临床病例，该患者因子宫内膜样腺癌已接受了三年的随访。在计算机断层扫描显示脐部有结节后，通过脐部活检确诊。该患者目前正在接受姑息化疗方案。
