Patel Jaykumar, Patel Chetna, Shah Akash, Shah Paras, Pandya Sajal, Sojitra Brijesh
Pharmacology, Government Medical College, Surat, Surat, IND.
Pharmacology, Government Medical College and New Civil Hospital, Surat, Surat, IND.
Cureus. 2024 Jul 18;16(7):e64873. doi: 10.7759/cureus.64873. eCollection 2024 Jul.
Ethambutol is a first-line chemotherapeutic agent, which is commonly used in combination with other drugs for the treatment of tuberculosis. Ethambutol-induced optic neuritis is a serious and rare side effect that is either dose or duration-related and causes progressive painless vision loss, and cecocentral scotomas in the visual field. A rare case of ethambutol-induced optic neuritis was reported in a 52-year-old female who was taking anti-tubercular treatment for pulmonary tuberculosis for five months. She presented with painless diminished vision in both eyes. The patient was diagnosed with a rare case of optic neuritis through various examination methods. Ethambutol was stopped and therapy was continued with oral prednisone, zinc, and vitamin B complex being started along with anti-TB treatment. She showed no marked improvement in visual parameters until the last follow-up. The patient died due to cardiopulmonary arrest as a consequence of pulmonary tuberculosis.
乙胺丁醇是一种一线化疗药物，通常与其他药物联合用于治疗结核病。乙胺丁醇引起的视神经炎是一种严重且罕见的副作用，与剂量或用药时长相关，会导致进行性无痛性视力丧失以及视野中心暗点。本文报告了一例罕见的乙胺丁醇引起的视神经炎病例，患者为一名52岁女性，因肺结核接受抗结核治疗五个月。她出现双眼无痛性视力下降。通过各种检查方法，该患者被诊断为罕见的视神经炎病例。停用乙胺丁醇，并继续进行治疗，同时开始口服泼尼松、锌和复合维生素B，并继续抗结核治疗。直到最后一次随访，她的视力参数均未显示出明显改善。该患者因肺结核导致心肺骤停而死亡。
