Department of Biological Sciences, College of Science, Sungkyunkwan University, Suwon 16419, South Korea.
Division of Life Sciences, Korea Polar Research Institute, Incheon, South Korea.
Mar Pollut Bull. 2024 Oct;207:116858. doi: 10.1016/j.marpolbul.2024.116858. Epub 2024 Aug 18.
Marine organisms' lipid metabolism contributes to marine ecosystems by producing a variety of lipid molecules. Historically, research focused on the lipid metabolism of the organisms themselves. Recent microbiome studies, however, have revealed that gut microbial communities influence the amount and type of lipids absorbed by organisms, thereby altering the organism's lipid metabolism. This has highlighted the growing importance of research on gut microbiota. This review highlights mechanisms by which gut microbiota facilitate lipid digestion and diversify the lipid pool in aquatic animals through the accelerated degradation of exogenous lipids and the transformation of lipid molecules. We also assess how environmental factors and pollutants, along with the innovative use of probiotics, interact with the gut microbiome to influence lipid metabolism within the host. We aim to elucidate the complex interactions between lipid metabolism and gut microbiota in aquatic animals by synthesizing current research and identifying knowledge gaps, providing a foundation for future explorations.
海洋生物的脂质代谢通过产生各种脂质分子为海洋生态系统做出贡献。历史上，研究主要集中在生物自身的脂质代谢上。然而，最近的微生物组研究表明，肠道微生物群落影响生物吸收的脂质的数量和类型，从而改变生物的脂质代谢。这凸显了研究肠道微生物群的重要性日益增加。本综述强调了肠道微生物群通过加速降解外源性脂质和转化脂质分子，促进脂质消化和使水生动物的脂质库多样化的机制。我们还评估了环境因素和污染物，以及益生菌的创新使用，如何与肠道微生物群相互作用，影响宿主内的脂质代谢。我们旨在通过综合当前的研究并确定知识空白，阐明水生动物中脂质代谢和肠道微生物群之间的复杂相互作用，为未来的探索提供基础。
