Department of Medicine, Aga Khan University, Karachi, Pakistan.
J Pak Med Assoc. 2024 Aug;74(8):1533-1537. doi: 10.47391/JPMA.10201.
Fungi rarely cause infective endocarditis but when they do, they are often associated with poor outcomes. Candida tropicalis accounts for only 10% of Candida endocarditis cases. A case of a 30-year-old male with a history of intravenous drug abuse was reported to the emergency department in August, 2021 with right-sided leg pain and fever for 3 days. A trans-thoracic echocardiogram showed a vegetation on the aortic valve and a computed tomography angiogram showed complete nonopacification of the right-sided common iliac artery and the superficial femoral artery just distal to its branching of the right profunda femoris artery. An emergent right iliofemoral embolectomy was done. Candida tropicalis was isolated from tissue and blood cultures. The patient was successfully treated with aortic valve replacement and intravenous caspofungin. The other reported cases of Candida tropicalis were reviewed and findings were compared with those reported in patients with Candida albicans and Candida parapsilosis endocarditis.
真菌很少引起感染性心内膜炎，但当它们引起感染性心内膜炎时，通常与不良预后相关。热带假丝酵母菌仅占假丝酵母菌心内膜炎病例的 10%。2021 年 8 月，一名 30 岁男性因静脉药物滥用史被送往急诊科，他出现右侧腿部疼痛和发热 3 天。经胸超声心动图显示主动脉瓣有赘生物，计算机断层血管造影显示右侧髂总动脉和股浅动脉完全不显影，就在其右侧股深动脉分支的远端。紧急进行了右髂股动脉取栓术。从组织和血液培养中分离出热带假丝酵母菌。该患者成功接受了主动脉瓣置换和静脉注射卡泊芬净治疗。对其他报道的热带假丝酵母菌病例进行了回顾，并与报道的白假丝酵母菌和近平滑假丝酵母菌心内膜炎患者的发现进行了比较。
