Alkundi Alamin, Momoh Rabiu
Diabetes and Endocrinology, East Kent Hospitals University Foundation Trust, Kent, GBR.
Critical Care, William Harvey Hospital, Ashford Kent, GBR.
Cureus. 2024 Jul 20;16(7):e64994. doi: 10.7759/cureus.64994. eCollection 2024 Jul.
Hypoglycaemic unawareness (HU) is more frequently described in relation to diabetics in the literature. We have noted that there is also an increasing reporting of HU in insulinoma cases. We report a hospital presentation for an incidental finding of hypoglycaemic unawareness in a gentleman in his fifties who was eventually diagnosed with insulinoma following biochemical studies, radiologic evaluation and histologic evaluation of an excised lesion between the pancreas and the spleen. We have reviewed existing literature evidence regarding the possible aetiologies and management options for this occurrence. More research studies to identify the epidemiology of this association and the determination of a protocol for increased detection of patients with insulinoma who display HU will need to be done.
低血糖无意识症（HU）在文献中更多地是与糖尿病患者相关联被描述。我们注意到，胰岛素瘤病例中关于HU的报告也在增加。我们报告了一例医院就诊情况，一名五十多岁的男性因偶然发现低血糖无意识症前来就诊，最终经生化检查、影像学评估以及对胰腺和脾脏之间切除病变的组织学评估后被诊断为胰岛素瘤。我们回顾了关于这种情况可能的病因和管理选择的现有文献证据。还需要进行更多研究以确定这种关联的流行病学，并确定用于增加检测出表现出HU的胰岛素瘤患者的方案。
