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通过动态葡萄糖监测系统揭示胰岛素瘤患者的低血糖无意识现象。

Hypoglycemia Unawareness in Insulinoma Revealed with Flash Glucose Monitoring Systems.

作者信息

Sugawa Taku, Murakami Takaaki, Yabe Daisuke, Kashima Riko, Tatsumi Makiko, Ooshima Shinobu, Joo Erina, Wada Keiko, Yoshizawa Atsushi, Masui Toshihiko, Nakamoto Yuji, Yamauchi Yuki, Kodama Yuzo, Iemura Yoshiki, Ogura Masahito, Yasoda Akihiro, Inagaki Nobuya

机构信息

Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Japan.

Department of Hepato-Biliary-Pancreatic Surgery and Transplantation, Kyoto University Graduate School of Medicine, Japan.

出版信息

Intern Med. 2018 Dec 1;57(23):3407-3412. doi: 10.2169/internalmedicine.1173-18. Epub 2018 Aug 10.

Abstract

The delayed diagnosis of insulinoma remains a clinical issue. One of the main causes of such a delay is hypoglycemia unawareness. A 53-year-old woman fell unconscious during postprandial exercises. Flash glucose monitoring (FGM) systems revealed glucose profiles with fasting hypoglycemia, which facilitated the clinical diagnosis of insulinoma even though she was unaware of her hypoglycemia. The preoperative comparison of the blood glucose values provided by FGM with those obtained from capillary blood were consistent. Thus, FGM may have potential utility in revealing the presence of insulinoma-induced hypoglycemia.

摘要

胰岛素瘤的延迟诊断仍然是一个临床问题。这种延迟的主要原因之一是低血糖无意识。一名53岁女性在餐后运动时失去意识。动态血糖监测(FGM)系统显示出空腹低血糖的血糖谱,这有助于胰岛素瘤的临床诊断,尽管她没有意识到自己的低血糖。FGM提供的血糖值与毛细血管血获得的血糖值术前比较是一致的。因此,FGM在揭示胰岛素瘤引起的低血糖方面可能具有潜在用途。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c40b/6306522/93f7e24ba649/1349-7235-57-3407-g001.jpg

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