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2
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Acyclovir-induced neuropsychosis successfully recovered after immediate hemodialysis in an end-stage renal disease patient.一名终末期肾病患者在立即进行血液透析后，阿昔洛韦诱发的神经精神障碍成功恢复。
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[Acyclovir-induced neurotoxicity and acute kidney injury in an elderly diabetic patient treated with valacyclovir: report of a case].[一名接受伐昔洛韦治疗的老年糖尿病患者出现阿昔洛韦诱导的神经毒性和急性肾损伤：病例报告]
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本文引用的文献

1
Acyclovir-induced neurotoxicity with a positive cerebrospinal fluid varicella zoster PCR result creating a management dilemma: a case report.阿昔洛韦引起的神经毒性，伴脑脊液单纯疱疹病毒 PCR 阳性结果，导致治疗困境：病例报告。
J Med Case Rep. 2020 Sep 18;14(1):156. doi: 10.1186/s13256-020-02498-3.
2
A case of acyclovir neurotoxicity presenting with atypical cerebrospinal fluid findings.一例表现为非典型脑脊液检查结果的阿昔洛韦神经毒性病例。
BMJ Case Rep. 2017 May 22;2017:bcr-2017-220372. doi: 10.1136/bcr-2017-220372.
3
Resolution of acyclovir-associated neurotoxicity with the aid of improved clearance estimates using a Bayesian approach: A case report and review of the literature.借助贝叶斯方法改进清除率估计来解决阿昔洛韦相关神经毒性：一例病例报告及文献综述
J Clin Pharm Ther. 2017 Jun;42(3):350-355. doi: 10.1111/jcpt.12520. Epub 2017 Mar 29.
4
Herpes zoster encephalopathy or acyclovir neurotoxicity: a management dilemma.带状疱疹性脑病或阿昔洛韦神经毒性：治疗困境
BMJ Case Rep. 2014 Apr 28;2014:bcr2013201941. doi: 10.1136/bcr-2013-201941.
5
KDIGO clinical practice guidelines for acute kidney injury.改善全球肾脏病预后组织（KDIGO）急性肾损伤临床实践指南
Nephron Clin Pract. 2012;120(4):c179-84. doi: 10.1159/000339789. Epub 2012 Aug 7.
6
The treatment of varicella-zoster virus infection and its complications.
Expert Opin Pharmacother. 2009 Apr;10(5):797-812. doi: 10.1517/14656560902808502.
7
Prevention of herpes zoster: recommendations of the Advisory Committee on Immunization Practices (ACIP).带状疱疹的预防：免疫实践咨询委员会（ACIP）的建议。
MMWR Recomm Rep. 2008 Jun 6;57(RR-5):1-30; quiz CE2-4.
8
Herpes zoster antivirals and pain management.带状疱疹抗病毒药物与疼痛管理。
Ophthalmology. 2008 Feb;115(2 Suppl):S13-20. doi: 10.1016/j.ophtha.2007.10.012.
9
Natural history and treatment of herpes zoster.带状疱疹的自然病史与治疗
J Pain. 2008 Jan;9(1 Suppl 1):S3-9. doi: 10.1016/j.jpain.2007.10.002.
10
Case report: acyclovir neurotoxicity and nephrotoxicity--the role for hemodialysis.病例报告：阿昔洛韦的神经毒性和肾毒性——血液透析的作用
Am J Med Sci. 1993 Jan;305(1):36-9. doi: 10.1097/00000441-199301000-00007.

一名糖尿病患者中阿昔洛韦引起的精神和肾脏不良反应：病例报告

Acyclovir-induced psychiatric and renal adverse effects in a diabetic patient: A case report.

作者信息

Roshanzamiri Soheil, Mousavizadeh Seyyedeh Azam, Razazzadeh Sareh, Ziaie Shadi

机构信息

Department of Clinical Pharmacy, School of Pharmacy Shahid Beheshti University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2024 Aug 19;12(8):e9310. doi: 10.1002/ccr3.9310. eCollection 2024 Aug.

DOI:10.1002/ccr3.9310
PMID:39161675
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11331032/
Abstract

Acyclovir can cause neurotoxicity and nephrotoxicity, especially in diabetic patients with renal impairment. Consider acyclovir dose adjustment, close monitoring of kidney function, and hemodialysis as a potential therapeutic option in such cases.

摘要

阿昔洛韦可引起神经毒性和肾毒性，尤其是在有肾功能损害的糖尿病患者中。在这种情况下，应考虑调整阿昔洛韦剂量、密切监测肾功能，并将血液透析作为一种潜在的治疗选择。