School of Health Service Management, Anhui Medical University, Hefei, Anhui, China.
Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Front Immunol. 2024 Aug 5;15:1444393. doi: 10.3389/fimmu.2024.1444393. eCollection 2024.
The present study aimed to assess influenza vaccine hesitancy and vaccine literacy levels among youth and adults in China, as well as the association between them.
An online cross-sectional survey was conducted in Mainland China. Participants' total vaccine literacy and three sub-dimension vaccine literacy (knowledge literacy, competence literacy, and decision-making literacy) were assessed by a validated vaccine literacy scale. Having received influenza vaccination in the past three years or intending to accept it in next influenza season indicates less influenza vaccine hesitancy.
Among 997 participants, a sub-optimal vaccine literacy was observed, with a mean score of 66.83 ± 10.27. Regression models 1-4 revealed that participants with middle ( 1.431, =0.039, 1.0182.010) or high ( 1.651, =0.006, 1.1572.354) total vaccine literacy, as well as those with high competence literacy ( 1.533, P=0.017, 1.0792.180), or high decision-making literacy ( 1.822, =0.001, 1.2612.632) were more likely to have been vaccinated against influenza at least once in past three years. However, those with a high knowledge literacy were associated with a lower influenza vaccine rate ( 0.676, =0.046, 0.4600.994). Regression models 5-8 revealed that participants with middle ( 1.661, =0.008, 1.1422.414) or high total vaccine literacy ( 2.645, =0.000, 1.7743.942), as well as those with middle ( 1.703, P=0.005, 1.1772.464) or high competence literacy ( 2.346, =0.000, 1.1593.461), or high decision-making literacy ( 2.294, =0.000, 1.5313.436) were more likely to express the willingness to receive the influenza vaccine in the next influenza season.
The participants' influenza vaccine hesitancy was negatively associated with their total vaccine literacy levels and two of the three sub-dimensions: competence literacy and decision-making literacy. Knowledge literacy suggested a positive or no relationship with influenza vaccine hesitancy.
本研究旨在评估中国青少年和成年人对流感疫苗的犹豫态度和疫苗素养水平，并探讨两者之间的关系。
本研究采用在线横断面调查的方式在中国内地进行。参与者的总疫苗素养和三个子维度疫苗素养（知识素养、能力素养和决策素养）通过经过验证的疫苗素养量表进行评估。过去三年中接种过流感疫苗或计划在下一个流感季节接种流感疫苗表示对流感疫苗的犹豫程度较低。
在 997 名参与者中，疫苗素养处于中下水平，平均得分为 66.83±10.27。模型 1-4 显示，具有中等（1.431，=0.039，1.0182.010）或较高（1.651，=0.006，1.1572.354）总疫苗素养、较高能力素养（1.533，P=0.017，1.0792.180）或较高决策素养（1.822，=0.001，1.2612.632）的参与者更有可能在过去三年中至少接种过一次流感疫苗。然而，具有较高知识素养的参与者接种流感疫苗的比例较低（0.676，=0.046，0.4600.994）。模型 5-8 显示，具有中等（1.661，=0.008，1.1422.414）或较高（2.645，=0.000，1.7743.942）总疫苗素养、中等（1.703，P=0.005，1.1772.464）或较高能力素养（1.703，P=0.005，1.1772.464）或较高决策素养（2.346，=0.000，1.1593.461）的参与者更有可能在下一个流感季节表示愿意接种流感疫苗。
参与者对流感疫苗的犹豫态度与他们的总疫苗素养水平以及三个子维度中的两个：能力素养和决策素养呈负相关。知识素养与流感疫苗犹豫态度呈正相关或无相关性。
