Assistant Professor, Department of General Medicine, ESIC Medical College and PGIMSR, Bengaluru, Karnataka, India.
Senior Resident, Department of General Medicine, ESIC Medical College and PGIMSR, Bengaluru, Karnataka, India.
J Assoc Physicians India. 2024 Aug;72(8):e35-e36. doi: 10.59556/japi.72.0596.
Systemic autoimmune disease contributes up to ~22% of cases of pericarditis with known etiology. Systemic lupus erythematosus (SLE) is a multisystem disease with a variety of clinical presentations and manifestations. Since the underlying mechanism for pericardial involvement differs with each systemic disease, this leads to poor understanding of its management. However, it is rare for acute pericarditis to be the leading symptom at the time of diagnosis of SLE, occurring in up to 1% of patients. This is a case report of a 21-year-old female who presented with breathlessness and pedal edema, who was previously misdiagnosed with tubercular pericarditis and was started on antitubercular treatment (ATT). Now she is diagnosed with autoimmune pericarditis with SLEoverlap syndrome. Pericarditis, being the most common cardiac manifestation of SLE, has an incidence ranging between 11 and 54%. Knowledge of such association is necessary to avoid misdiagnosis.
系统性自身免疫性疾病导致已知病因的心包炎的比例高达 22%左右。系统性红斑狼疮（SLE）是一种多系统疾病，具有多种临床表现。由于每种系统性疾病心包受累的潜在机制不同，因此导致其治疗效果不佳。然而，急性心包炎作为 SLE 诊断时的主要症状较为罕见，发生率在 1%以下。这是一例 21 岁女性患者的病例报告，她以呼吸困难和足踝水肿为主要症状，曾被误诊为结核性心包炎，并接受了抗结核治疗（ATT）。现在她被诊断为重叠性系统性红斑狼疮伴自身免疫性心包炎。心包炎是 SLE 最常见的心脏表现，其发生率在 11%至 54%之间。了解这种关联对于避免误诊是必要的。
