Kern Medical, Bakersfield, CA, USA.
J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221077832. doi: 10.1177/23247096221077832.
In systemic lupus erythematosus (SLE), cardiac manifestations are known to be present in up to 50% of patients. However, it is rare for acute pericarditis to be the leading symptom at the time of diagnosis of SLE occurring in up to 1% of patients. We present a case series in which 3 patients with no prior history of SLE presented with acute pericarditis. This was found to be the leading manifestation of their disease, which ultimately led to the diagnosis of SLE. These patients were initially treated with nonsteroidal anti-inflammatory drugs and colchicines; however, steroids and disease-modifying anti-rheumatologic agents were ultimately added to their medical therapy.
在系统性红斑狼疮（SLE）中，已知多达 50%的患者存在心脏表现。然而，急性心包炎作为 SLE 诊断时的主要症状较为罕见，发生率高达 1%。我们报告了三例无 SLE 既往史的患者，他们均以急性心包炎为首发表现。心包炎是导致 SLE 的主要表现，最终确诊为 SLE。这些患者最初接受了非甾体抗炎药和秋水仙碱治疗；然而，最终他们的药物治疗中添加了类固醇和改善病情的抗风湿药物。
