Ment L R, Duncan C C, Stewart W B
Pediatr Neurosci. 1985;12(3):168-74. doi: 10.1159/000120242.
The incidence of major neurodevelopmental handicaps in the survivors of newborn special care has remained essentially unchanged over the past decade despite the development of sophisticated perinatal care. Preterm infants with parenchymal involvement of intraventricular hemorrhage and neonates of all gestational ages with cerebral infarction are believed to be at higher risk for both neurologic and developmental abnormalities than infants without these problems. Both lesions are thought secondary to alterations in cerebral blood flow to the developing brain, and many infants demonstrate evidence for both hemorrhage and ischemic insult.
尽管围产期护理技术不断发展，但在过去十年中，新生儿重症监护幸存者中主要神经发育障碍的发生率基本保持不变。与没有这些问题的婴儿相比，患有脑室内出血实质受累的早产儿和所有孕周的患有脑梗死的新生儿被认为发生神经和发育异常的风险更高。这两种病变都被认为是发育中大脑的脑血流改变所致，许多婴儿都有出血和缺血性损伤的证据。
