吸入莫拉司亭治疗自身免疫性肺泡蛋白沉积症（aPAP）：IMPALA试验的通俗易懂总结 - Suppr | 超能文献

Inhaled molgramostim therapy for the treatment of autoimmune pulmonary alveolar proteinosis (aPAP): a plain language summary of the IMPALA trial.

作者信息

Trapnell Bruce C

机构信息

Translational Pulmonary Science Center, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

出版信息

Hosp Pract (1995). 2024 Aug;52(3):47-63. doi: 10.1080/21548331.2024.2367955. Epub 2024 Aug 21.

DOI:10.1080/21548331.2024.2367955

Abstract

摘要

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。

相似文献

1

Inhaled molgramostim therapy for the treatment of autoimmune pulmonary alveolar proteinosis (aPAP): a plain language summary of the IMPALA trial.吸入莫拉司亭治疗自身免疫性肺泡蛋白沉积症（aPAP）：IMPALA试验的通俗易懂总结

Hosp Pract (1995). 2024 Aug;52(3):47-63. doi: 10.1080/21548331.2024.2367955. Epub 2024 Aug 21.

2

Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar Proteinosis.吸入莫拉司亭治疗自身免疫性肺性肺泡蛋白沉积症。

N Engl J Med. 2020 Oct 22;383(17):1635-1644. doi: 10.1056/NEJMoa1913590. Epub 2020 Sep 7.

3

Inhaled GM-CSF for Pulmonary Alveolar Proteinosis.吸入 GM-CSF 治疗肺泡蛋白沉积症。

N Engl J Med. 2019 Sep 5;381(10):923-932. doi: 10.1056/NEJMoa1816216.

4

Inhaled recombinant GM-CSF reduces the need for whole lung lavage and improves gas exchange in autoimmune pulmonary alveolar proteinosis patients.吸入重组 GM-CSF 可减少全肺灌洗的需求并改善自身免疫性肺泡蛋白沉积症患者的气体交换。

Eur Respir J. 2024 Jan 4;63(1). doi: 10.1183/13993003.01233-2023. Print 2024 Jan.

5

Better approach for autoimmune pulmonary alveolar proteinosis treatment: inhaled or subcutaneous granulocyte-macrophage colony-stimulating factor: a meta-analyses.治疗自身免疫性肺泡蛋白沉积症的更好方法：吸入或皮下粒细胞-巨噬细胞集落刺激因子：荟萃分析。

Respir Res. 2018 Aug 31;19(1):163. doi: 10.1186/s12931-018-0862-4.

6

Autoimmune pulmonary alveolar proteinosis in an adolescent successfully treated with inhaled rhGM-CSF (molgramostim).青少年自身免疫性肺泡蛋白沉积症经吸入重组人粒细胞巨噬细胞集落刺激因子（莫拉司亭）成功治疗

Respir Med Case Rep. 2018 Feb 23;23:167-169. doi: 10.1016/j.rmcr.2018.02.005. eCollection 2018.

7

Quantitative analysis of longitudinal response to aerosolized granulocyte-macrophage colony-stimulating factor in two adolescents with autoimmune pulmonary alveolar proteinosis.两名自身免疫性肺泡蛋白沉积症青少年对雾化粒细胞-巨噬细胞集落刺激因子纵向反应的定量分析。

Chest. 2009 Mar;135(3):842-848. doi: 10.1378/chest.08-1317.

8

Direct evidence that GM-CSF inhalation improves lung clearance in pulmonary alveolar proteinosis.直接证据表明 GM-CSF 吸入可改善肺泡蛋白沉积症患者的肺部清除率。

Respir Med. 2012 Feb;106(2):284-93. doi: 10.1016/j.rmed.2011.10.019. Epub 2011 Nov 22.

9

Pulmonary alveolar proteinosis: time to shift?肺泡蛋白沉积症：是时候做出改变了吗？

Expert Rev Respir Med. 2015 Jun;9(3):337-49. doi: 10.1586/17476348.2015.1035259. Epub 2015 Apr 12.

10

Successful granulocyte-macrophage colony-stimulating factor inhalation therapy for recurrent autoimmune pulmonary alveolar proteinosis after lung transplantation: A case report.肺移植术后复发性自身免疫性肺泡蛋白沉积症的成功粒细胞-巨噬细胞集落刺激因子吸入治疗：一例报告

Respir Investig. 2025 Jan;63(1):180-182. doi: 10.1016/j.resinv.2024.12.001. Epub 2025 Jan 4.

引用本文的文献

1

Dyspnea and Deception: Overcoming Diagnostic Hurdles in Pulmonary Alveolar Proteinosis.呼吸困难与误诊：克服肺泡蛋白沉积症的诊断障碍

Cureus. 2025 May 21;17(5):e84562. doi: 10.7759/cureus.84562. eCollection 2025 May.