Abbasi Elahe, Hajhashemy Zahra, Askari Gholamreza, Saneei Parvane
Student Research Committee, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
Nutrition and Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran.
Clin Nutr Res. 2024 Jul 30;13(3):201-213. doi: 10.7762/cnr.2024.13.3.201. eCollection 2024 Jul.
This systematic review and meta-analysis of randomized controlled trials (RCTs) aimed to test our hypothesis that herbal tea may improve anthropometric parameters, metabolic factors, and hormone levels in women with polycystic ovarian syndrome (PCOS). A literature search was conducted on Information Sciences Institute, Medline (PubMed), Scopus, Embase, and Google Scholar, up to March 2023 without applying language or date restrictions. RCTs that assigned herbal tea vs. placebo on PCOS women and evaluated changes in anthropometric measurements, metabolic indices, or hormonal profiles were included. Six RCTs with 235 PCOS women (119 in the intervention and 116 in the control group) were included. Meta-analysis showed that herbal tea consumption led to significant decreases in weight (weighted mean difference [WMD], -2.02 kg; 95% confidence interval [CI], -3.25, -0.80), body mass index (BMI) (WMD, -0.88 kg/m; 95% CI, -1.47, -0.28) and fasting blood glucose (FBG) (WMD, -6.47 mg/dL; 95% CI, -8.49, -4.45), compared to the control group. Herbal tea supplementation has also significantly increased follicle-stimulating hormone (FSH) concentration (WMD, 0.56 IU/L; 95% CI, 0.17, 0.95). Meanwhile, the effect of herbal tea on the waist/hip ratio, hip circumference, waist circumference, body fat, fasting insulin, FBG/insulin ratio, luteinizing hormone, total testosterone, and dehydroepiandrosterone sulfate was not significant. Herbal tea might be a potential supplemental therapy to manage weight, BMI, FBG, and FSH in PCOS women. Further large randomized clinical trials are recommended to affirm these findings.
本项对随机对照试验（RCT）的系统评价和荟萃分析旨在检验我们的假设，即花草茶可能改善多囊卵巢综合征（PCOS）女性的人体测量参数、代谢因素和激素水平。截至2023年3月，在信息科学研究所、医学期刊数据库（PubMed）、Scopus、Embase和谷歌学术上进行了文献检索，检索时未设置语言或日期限制。纳入了将花草茶与安慰剂分配给PCOS女性并评估人体测量、代谢指标或激素谱变化的随机对照试验。纳入了六项随机对照试验，共235名PCOS女性（干预组119名，对照组116名）。荟萃分析表明，与对照组相比，饮用花草茶可显著降低体重（加权平均差[WMD]，-2.02 kg；95%置信区间[CI]，-3.25，-0.80）、体重指数（BMI）（WMD，-0.88 kg/m²；95% CI，-1.47，-0.28）和空腹血糖（FBG）（WMD，-6.47 mg/dL；95% CI，-8.49，-4.45）。补充花草茶还可显著提高促卵泡激素（FSH）浓度（WMD，0.56 IU/L；95% CI，0.17，0.95）。同时，花草茶对腰臀比、臀围、腰围、体脂、空腹胰岛素、FBG/胰岛素比值、促黄体生成素、总睾酮和硫酸脱氢表雄酮水平的影响不显著。花草茶可能是管理PCOS女性体重、BMI、FBG和FSH的一种潜在补充疗法。建议进一步开展大型随机临床试验以证实这些发现。
