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一例免疫功能正常成年人的结痂性疥疮罕见病例:病例报告。

An unusual case of crusted scabies in an immunocompetent adult: A case report.

作者信息

Agyei Martin, Opare-Addo Priscilla Abrafi, Ofori Afua, Kyem Gloria, Gyabaah Solomon, Asare-Bediako Serwaa

机构信息

Department of Internal Medicine Komfo Anokye Teaching Hospital Kumasi Ghana.

School of Medicine and Dentistry Kwame Nkrumah University of Science and Technology Kumasi Ghana.

出版信息

Clin Case Rep. 2024 Aug 20;12(8):e9325. doi: 10.1002/ccr3.9325. eCollection 2024 Aug.

Abstract

KEY CLINICAL MESSAGE

Although rare, crusted scabies can affect immunocompetent individuals with no identifiable risk factors. A high index of suspicion, regardless of an individual's immunological status or absence of traditional risk factors, should be maintained by health professionals to facilitate prompt referral to a dermatologist.

ABSTRACT

Crusted scabies is an uncommon variant of human scabies characterized by extensive crusted and scaly hyperkeratotic papules, and plaques resulting from profound proliferation of mites in the skin. It is highly contagious and typically occurs in immunocompromised individuals. Reports of cases in healthy adults are rare. It is often resistant to routine treatment. We report a case of a 30-year-old immunocompetent male who presented to us with an extensive pruritic papular rash that started in the inter-digital web spaces of his hands. Within 3 months from onset, the lesions progressed, and became hyperkeratotic, scaly, non-pruritic, spreading to involve his entire body (sparing his face only). Crusty scabies was eventually diagnosed and treated by a dermatologist after months of misdiagnosis at peripheral facilities. Although rare, crusted scabies can affect immunocompetent individuals. A high index of suspicion is required, regardless of immunological status. Among immunocompetent individuals, a thorough search for traditional risk factors is imperative.

摘要

关键临床信息

尽管罕见,但结痂性疥疮可影响无明显危险因素的免疫功能正常个体。医护人员应保持高度警惕,无论个体免疫状态如何或是否存在传统危险因素,以便及时转诊至皮肤科医生处。

摘要

结痂性疥疮是人类疥疮的一种罕见变种,其特征为广泛的结痂、鳞屑性角化过度丘疹以及因螨虫在皮肤中大量增殖而形成的斑块。它具有高度传染性,通常发生在免疫功能低下的个体中。健康成年人中病例报告罕见。它通常对常规治疗有抗性。我们报告一例30岁免疫功能正常男性病例,该患者双手指间皮肤出现广泛瘙痒性丘疹皮疹。起病3个月内,皮损进展,变为角化过度、鳞屑性、无瘙痒,蔓延至全身(仅面部未累及)。在外周医疗机构误诊数月后,最终由皮肤科医生诊断并治疗为结痂性疥疮。尽管罕见,但结痂性疥疮可影响免疫功能正常个体。无论免疫状态如何,都需要高度怀疑。在免疫功能正常个体中,必须全面排查传统危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b2/11333851/5b2dd4d6a836/CCR3-12-e9325-g004.jpg

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