Forkhead Box O (FOXO) signaling in NSCLC: pathways to targeted therapies.
作者信息
Thangavelu Lakshmi, Andreoli Pinto Terezinha de Jesus, Pathak Sachchidanand, Tiwari Abhishek, Tiwari Varsha, Gupta Gaurav, Pant Kumud, Gupta Saurabh, Shahwan Moyad
机构信息
Centre for Global Health Research, Saveetha Medical College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, India.
Department of Pharmacy, Faculty of Pharmaceutical Sciences, University of Sao Paulo, Professor Lineu Prestes Street, Sao Paulo 05508-000, Brazil.
出版信息
EXCLI J. 2024 May 31;23:860-861. doi: 10.17179/excli2024-7272. eCollection 2024.
Abstract
摘要
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本文引用的文献
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The FoxO4/DKK3 axis represses IFN-γ expression by Th1 cells and limits antimicrobial immunity.FoxO4/DKK3 轴通过 Th1 细胞抑制 IFN-γ 的表达并限制抗菌免疫。
J Clin Invest. 2022 Sep 15;132(18):e147566. doi: 10.1172/JCI147566.
2
FOXO1 and FOXO3a sensitize non-small-cell lung cancer cells to cisplatin-induced apoptosis independent of Bim.FOXO1 和 FOXO3a 使非小细胞肺癌细胞对顺铂诱导的细胞凋亡敏感，而不依赖于 Bim。
Acta Biochim Biophys Sin (Shanghai). 2020 Dec 29;52(12):1348-1359. doi: 10.1093/abbs/gmaa129.
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MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate.MCC1019，一种新型、强效的抗癌候选药物，是Polo样激酶1的Polo盒结构域的选择性抑制剂。
Acta Pharm Sin B. 2019 Sep;9(5):1021-1034. doi: 10.1016/j.apsb.2019.02.001. Epub 2019 Feb 10.
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FoxO3a inhibiting expression of EPS8 to prevent progression of NSCLC: A new negative loop of EGFR signaling.FoxO3a 通过抑制 EPS8 的表达来阻止 NSCLC 的进展：EGFR 信号的新负反馈环。
EBioMedicine. 2019 Feb;40:198-209. doi: 10.1016/j.ebiom.2019.01.053. Epub 2019 Feb 7.
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FoxO3 an important player in fibrogenesis and therapeutic target for idiopathic pulmonary fibrosis.FoxO3 是肝纤维化发病机制中的一个重要因子，也是特发性肺纤维化的一个治疗靶点。
EMBO Mol Med. 2018 Feb;10(2):276-293. doi: 10.15252/emmm.201606261.
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Therapeutic Targeting of Nuclear Export Inhibition in Lung Cancer.肺癌中核输出抑制的治疗靶向作用
J Thorac Oncol. 2017 Sep;12(9):1446-1450. doi: 10.1016/j.jtho.2017.06.013. Epub 2017 Jun 21.
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Braz J Med Biol Res. 2017 Jan 5;50(1):e5794. doi: 10.1590/1414-431X20165794.
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