Goza Shelby D, Lebhar Michael S, Sullivan John M, Waetjen Eric, Walker Marc E
Division of Plastic and Reconstructive Surgery, University of Mississippi Medical Center, Jackson, MS.
J Hand Surg Glob Online. 2024 Jun 5;6(4):590-592. doi: 10.1016/j.jhsg.2024.05.005. eCollection 2024 Jul.
Tumoral calcinosis (TC) is a rare condition defined by the accumulation of calcium salts in soft tissues surrounding joints, most commonly large joints. Chronic joint inflammation in the setting of local hyperphosphatemia leads to interruption and dysfunction of tissue repair and generates breakdown products that subsequently calcify and accumulate. We present a case of a 42-year-old man with a history of end-stage renal disease on dialysis presenting to the clinic with a painless digital mass of his right long finger at the proximal interphalangeal joint. Our initial impression was a splinter abscess based on presentation and patient history. Although our patient's presentation of traumatic, painless TC of the hand secondary to end-stage renal disease is rare, the pathogenic mechanisms behind TC support this presentation. The authors recommend including TC within the differential of presentations similar to that of chronic abscess or giant cell tumor, especially when their medical history includes end-stage renal disease.
肿瘤性钙化（TC）是一种罕见的病症，其定义为关节周围软组织（最常见于大关节）中钙盐的蓄积。局部高磷血症情况下的慢性关节炎症会导致组织修复中断和功能障碍，并产生随后钙化和蓄积的分解产物。我们报告一例42岁男性病例，该患者有终末期肾病透析病史，因右手中指近端指间关节出现无痛性肿块前来就诊。根据临床表现和患者病史，我们最初的诊断是碎屑性脓肿。尽管我们的患者因终末期肾病继发手部创伤性无痛性肿瘤性钙化的表现很罕见，但肿瘤性钙化背后的致病机制支持了这种表现。作者建议在鉴别诊断时，将肿瘤性钙化纳入类似于慢性脓肿或巨细胞瘤的表现中，尤其是当患者病史包括终末期肾病时。
