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甲状腺外科学中炎症生物标志物与甲状腺手术围手术期并发症的有力整合。

Cogent integration of inflammatory biomarkers and perioperative complications of thyroid surgery in thyroidology.

机构信息

Giresun University, Faculty of Medicine, Department of Anesthesiology and Reanimation - Giresun, Turkey.

Giresun University, Faculty of Medicine, Division of Endocrine Surgery - Giresun, Turkey.

出版信息

Rev Assoc Med Bras (1992). 2024 Aug 16;70(7):e20240378. doi: 10.1590/1806-9282.20240378. eCollection 2024.

Abstract

OBJECTIVE

Back to the sources, postoperative nausea and vomiting, hypo- and hypertension, heart rate alterations, and hypoxemia due to laryngospasm might be considered perioperative complications.

METHODS

This cross-sectional study was conducted at an Education and Research Hospital between January 2018 and June 2023. The study included a total of 437 cases of thyroid surgery. The demographic data such as age, sex, co-morbidities of the instances, hypotension, hypertension, bradycardia, hypoxemia, and postoperative nausea and vomiting, as well as laboratory data were obtained and analyzed.

RESULTS

Of 437 cases, 334 (76%) were females and 103 (24%) were males, with a mean age of 51.83±11.91 years and 55.32±11.87 years, respectively. No statistical significance was realized between the complications, co-morbid diseases, and age. Notably, no liaison between the complications after awakening from the anesthesia and preoperative laboratory parameters was discerned. However, a high but no significant relationship was revealed between the platelet-to-lymphocyte ratio (P/L) in cases with hypoxemia and hypotension. Finally, no significance between laboratory values, bradycardia, hypertension, and postoperative nausea and vomiting was distinguished.

CONCLUSION

We postulate that the so-called inflammatory biomarkers measured at the time of preoperative examination in the blood count concept selectively do not enrich for anticipating complications that arise in the perioperative echelon.

摘要

目的

回到源头,术后恶心和呕吐、低血压和高血压、心率改变以及由于喉痉挛导致的低氧血症可能被视为围手术期并发症。

方法

这是一项在 2018 年 1 月至 2023 年 6 月期间在一所教育和研究医院进行的横断面研究。该研究共纳入了 437 例甲状腺手术患者。收集并分析了患者的人口统计学数据,如年龄、性别、合并症、低血压、高血压、心动过缓、低氧血症和术后恶心呕吐,以及实验室数据。

结果

在 437 例患者中,334 例(76%)为女性,103 例(24%)为男性,平均年龄分别为 51.83±11.91 岁和 55.32±11.87 岁。并发症、合并症和年龄之间无统计学差异。值得注意的是,麻醉苏醒后并发症与术前实验室参数之间没有联系。然而,发现低氧血症和低血压患者的血小板与淋巴细胞比值(P/L)之间存在高度但无统计学意义的关系。最后,未发现实验室值、心动过缓、高血压和术后恶心呕吐之间有显著差异。

结论

我们假设在术前检查时测量的所谓炎症生物标志物在血常规概念中选择性地不能预测围手术期发生的并发症。

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