Adem Endris Yassin, Abdu Kedir Yesuf, Abate Solomon Getachew
School of Mechanical and Chemical Engineering, Kombolcha Institute Technology, Wollo University, p.o.box 208, Ethiopia.
Heliyon. 2024 Jul 26;10(15):e34687. doi: 10.1016/j.heliyon.2024.e34687. eCollection 2024 Aug 15.
Medicinal plants Highly aromatic crude materials are utilized for treating warts as an alternative medicine to surgical treatment because they can be permanently removed from the body. Thus, this investigation aimed to extract plant material from leaves, describe the phytochemical screening, analyze anti-microbial activities, determine the functional groups in FTIR, and identify the chemical compounds in GC-MS. The PH, specific gravity, and viscosity of the crude extracts of were determined at 4.5, 0.79, and 0.49, respectively. Analyze the solubility of crude extracts; ethanol can dissolve while water does not. Flavonoids, alkaloids, phenols, tannins, and saponins were also present in the phytochemical screening tests of the extracts, triterpenoids, terpenoids, and steroids were not present in the crude extract. Flavonoids, alkaloids, phenols, tannins, and saponins are the primary phytochemical components found in therapeutic plant material. The procera crude extracts analyzed for functional groups by FT-IR contained a hydroxyl group, alkane, carbonyl, aldehyde, ketone, phenols, ester, alcohol, and methylene. The chemical compounds analyzed by GC-MS of crude material were found to have 22 main compounds. Of 22 compounds, 5 compounds are active ingredients for the applications of medical purposes. The bioactive compounds found in the plant extract are neophytadiene, hexahydrofarnesyl, lanosterol, 2,4-dimethylbenzo [H]quinolone, and squalene. Those bioactive compounds have anti-bacterial, analgesic, antipyretic, anti-inflammatory, antimicrobial, antioxidant, antiviral, and anti-cancer properties. In an in vitro antimicrobial activity test, the crude extract effectively inhibited more gram-positive bacteria than gram-negative bacteria. This collective reason is why the traditional therapist uses this plant for the treatment of warts.
药用植物 高度芳香的原材料被用作治疗疣的替代药物，以取代手术治疗，因为它们可以从体内永久去除。因此，本研究旨在从叶片中提取植物材料，描述植物化学筛选，分析抗菌活性，确定傅里叶变换红外光谱（FTIR）中的官能团，并通过气相色谱-质谱联用仪（GC-MS）鉴定化合物。提取物粗提物的pH值、比重和粘度分别测定为4.5、0.79和0.49。分析粗提物的溶解度；乙醇可溶解，而水则不能。在提取物的植物化学筛选试验中还存在黄酮类、生物碱、酚类、单宁和皂苷，粗提物中不存在三萜类、萜类和甾体类。黄酮类、生物碱、酚类、单宁和皂苷是治疗性植物材料中发现的主要植物化学成分。通过傅里叶变换红外光谱（FT-IR）分析官能团的普罗克勒粗提物含有羟基、烷烃、羰基、醛基、酮基、酚类、酯类、醇类和亚甲基。通过气相色谱-质谱联用仪（GC-MS）分析的粗材料的化合物被发现有22种主要化合物。在22种化合物中，有5种化合物是用于医疗目的的活性成分。在植物提取物中发现的生物活性化合物是新植二烯、六氢法呢基、羊毛甾醇、2,4-二甲基苯并[H]喹诺酮和角鲨烯。这些生物活性化合物具有抗菌、止痛、退热、抗炎、抗菌、抗氧化、抗病毒和抗癌特性。在体外抗菌活性试验中，粗提物对革兰氏阳性菌的抑制作用比对革兰氏阴性菌更有效。综合这些原因，这就是传统治疗师使用这种植物治疗疣的原因。
