Hayes Alexander, Wilson Mark, Gontsarova Anastassia, Carswell Christopher
Imperial College London, Department of Brain Sciences, London, UK
Neurosurgery, Imperial College Healthcare NHS Trust, London, UK.
Pract Neurol. 2025 Jan 16;25(1):70-74. doi: 10.1136/pn-2024-004240.
Vestibular schwannoma is a common benign tumour that may cause local complications. However, vestibular schwannoma has a known association with communicating hydrocephalus presenting with symptoms of normal pressure hydrocephalus and requiring treatment by ventricular shunting or tumour resection. We report a 79-year-old woman who presented with subacute gait apraxia, cognitive impairment and urinary incontinence. CT and MR imaging identified a 20 mm vestibular schwannoma and communicating hydrocephalus; her cerebrospinal fluid (CSF) protein was elevated. Her symptoms improved following ventriculoperitoneal shunt insertion. The mechanism by which non-obstructing vestibular schwannoma causes hydrocephalus is unclear, but hyperproteinorrachia is probably important, likely by impeding CSF resorption.
前庭神经鞘瘤是一种常见的良性肿瘤,可能会引起局部并发症。然而,前庭神经鞘瘤与交通性脑积水有关,可表现为正常压力脑积水的症状,需要通过脑室分流或肿瘤切除进行治疗。我们报告一名79岁女性,她出现亚急性步态失用、认知障碍和尿失禁。CT和磁共振成像显示有一个20毫米的前庭神经鞘瘤和交通性脑积水;她的脑脊液蛋白升高。在插入脑室腹腔分流管后,她的症状有所改善。非阻塞性前庭神经鞘瘤导致脑积水的机制尚不清楚,但高蛋白脑脊液可能很重要,可能是通过阻碍脑脊液吸收起作用。