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NSF 对人工釉质龋的再矿化作用。

Remineralizing effect of NSF on artificial enamel caries.

机构信息

Dental Prosthesis Manufacture Technology Department, Faculty of Applied Health Sciences Technology, Pharos University, Alexandria, Egypt.

Alexandria Dental Research Center, Ministry of Health and Population, Alexandria, Egypt.

出版信息

BMC Oral Health. 2024 Aug 22;24(1):975. doi: 10.1186/s12903-024-04668-x.

Abstract

INTRODUCTION

Nanotechnology offers new approaches and endless opportunities for remineralizing tooth decay without being toxic or causing allergies. This study aimed to determine the effect of nanosilver fluoride (NSF) on the remineralization potential of enamel caries-like lesions compared to 5% sodium fluoride varnish in permanent teeth.

METHODS

Fifteen teeth (molars and premolars) were gathered, cleaned, and polished using a scaler. After sectioning the teeth mesiodistally and removing the roots, the thirty specimens were subjected to a demineralized solution to induce early enamel lesions and then assigned randomly into two equal groups. The test materials were applied, and then all the specimens were subjected to a pH cycling model for 30 days. DIAGNOdent and surface roughness were investigated, and an evaluation of the enamel Ca and P weight% for Ca/P ratio calculation was done using SEM-EDX to analyze the specimens at the end of the study. The data were analyzed using an independent t-test.

RESULTS

The mean values for the DIAGNOdent measurements for NSF and NaF at baseline and after demineralization were not significantly different (p > 0.05). After treatment, NaF varnish showed a significantly higher mean DIAGNOdent measurement (11.8 ± 5.80) than NSF (4.7 ± 1.6). The mean surface roughness of the NaF group (1.64 ± 0.39) was much higher than NSF's mean surface roughness (1.07 ± 0.21). Specimens treated with NSF had statistically significant smoother surfaces (p < 0.001). The NSF group had a higher mean Ca/P ratio (2.9 ± 0.35) than NaF (2.2 ± 0.11). This difference was statistically significant (p = 0.012).

CONCLUSION

The study reveals that nano silver fluoride is a more effective treatment than sodium fluoride varnish in enhancing teeth's clinical characteristics, particularly in terms of mineral content and surface roughness, suggesting it could be an improved strategy to prevent dental caries and maintain enamel integrity.

摘要

简介

纳米技术为牙齿脱矿提供了新的方法和无尽的机会,且不会产生毒性或引起过敏。本研究旨在比较纳米氟化银(NSF)和 5%氟化钠涂料对恒牙龋样病变再矿化潜力的影响。

方法

收集 15 颗(磨牙和前磨牙)牙齿,用牙周刮治器清洁和抛光。牙齿颊舌向纵剖并去除根后,将 30 个标本置于脱矿液中诱导早期牙釉质病变,然后随机分为两组。实验组应用试验材料,所有标本均进行 30 天 pH 循环模型。使用 DIAGNOdent 检测并测量表面粗糙度,用扫描电镜-能谱仪(SEM-EDX)检测标本结束时的釉质 Ca 和 P 重量%,以计算 Ca/P 比值。采用独立 t 检验分析数据。

结果

NSF 和 NaF 在基线和脱矿后的 DIAGNOdent 测量均值无统计学差异(p>0.05)。治疗后,NaF 组的 DIAGNOdent 测量值(11.8±5.80)显著高于 NSF 组(4.7±1.6)。NaF 组的平均表面粗糙度(1.64±0.39)明显高于 NSF 组(1.07±0.21)。NSF 组表面更光滑,差异有统计学意义(p<0.001)。NSF 组的 Ca/P 比值(2.9±0.35)高于 NaF 组(2.2±0.11),差异有统计学意义(p=0.012)。

结论

本研究表明,纳米氟化银是一种比氟化钠涂料更有效的治疗方法,可增强牙齿的临床特征,尤其是在矿物质含量和表面粗糙度方面,提示其可能是预防龋齿和维持釉质完整性的一种改进策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61fb/11340118/9ff9989c9fe6/12903_2024_4668_Fig1_HTML.jpg

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