Reversing the understanding of irreversibly sickled cells.
作者信息
Kim-Shapiro Daniel B
机构信息
Department of Physics and the Translational Science Center, Wake Forest University, Winston-Salem, North Carolina.
出版信息
Biophys J. 2024 Nov 5;123(21):3653-3654. doi: 10.1016/j.bpj.2024.08.013. Epub 2024 Aug 22.
Abstract
摘要
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1
Reversing the understanding of irreversibly sickled cells.扭转对不可逆镰状细胞的认识。
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Nitrendipine, nifedipine and verapamil inhibit the in vitro formation of irreversibly sickled cells.尼群地平、硝苯地平和维拉帕米可抑制体外不可逆镰状细胞的形成。
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Study of irreversibly sickled cells in an animal model.动物模型中不可逆镰状细胞的研究。
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6
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Relationship of glutathione levels and Heinz body formation to irreversibly sickled cells in sickle cell anemia.镰状细胞贫血中谷胱甘肽水平和海因茨小体形成与不可逆镰状细胞的关系。
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Organizational differences in the membrane proteins of normal and irreversibly sickled erythrocytes.正常和不可逆镰状红细胞膜蛋白的组织差异。
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Blood samples collected under venous oxygen pressure from patients with sickle cell disease contain a significant number of a new type of reversibly sickled cells: constancy of the percentage of sickled cells in individual patients during steady state.在静脉血氧压力下从镰状细胞病患者采集的血样中含有大量新型可逆性镰状细胞：稳态期间个体患者镰状细胞百分比恒定。
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本文引用的文献
1
Novel single-cell measurements suggest irreversibly sickled cells are neither dense nor dehydrated.新的单细胞测量结果表明，不可逆转镰变的细胞既不致密也没有脱水。
Biophys J. 2024 Nov 5;123(21):3750-3758. doi: 10.1016/j.bpj.2024.09.024. Epub 2024 Sep 26.
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Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000-2021: a systematic analysis from the Global Burden of Disease Study 2021.全球、区域和国家镰状细胞病的患病率和死亡负担，2000-2021 年：2021 年全球疾病负担研究的系统分析。
Lancet Haematol. 2023 Aug;10(8):e585-e599. doi: 10.1016/S2352-3026(23)00118-7. Epub 2023 Jun 15.
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Sickle cell dehydration: Pathophysiology and therapeutic applications.镰状细胞脱水：病理生理学与治疗应用
Clin Hemorheol Microcirc. 2018;68(2-3):187-204. doi: 10.3233/CH-189007.
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The irreversibly sickled cell: a perspective.不可逆性镰状细胞：一种观点。
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A specific chemical difference between the globins of normal human and sickle-cell anaemia haemoglobin.正常人类血红蛋白和镰状细胞贫血血红蛋白中珠蛋白的特定化学差异。
Nature. 1956 Oct 13;178(4537):792-4. doi: 10.1038/178792a0.
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Deformability of oxygenated irreversibly sickled cells.氧合不可逆镰状细胞的可变形性
J Clin Invest. 1980 Jan;65(1):189-96. doi: 10.1172/JCI109650.
7
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Irreversibly sickled erythrocytes in sickle cell anemia: a quantitative reappraisal.镰状细胞贫血中不可逆镰状红细胞：定量重新评估
Am J Hematol. 1985 Sep;20(1):17-23. doi: 10.1002/ajh.2830200104.
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Sickle cell hemoglobin polymerization.镰状细胞血红蛋白聚合。
Adv Protein Chem. 1990;40:63-279. doi: 10.1016/s0065-3233(08)60287-9.
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