Ali Moatazbellah I, Rashad Mahmoud M, Alzain Nasser M, Al-Awad Feras A, Alzaharani Mohammed A, Alshamarani Abdulsalam S, Almuqahwi Mohammed S, Afifi Shrief Y
Department of Neuropsychiatry, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt.
Department of Psychiatry, Erada Complex for Mental Health, Eastern Health Cluster, Dammam, Saudi Arabia.
J Family Community Med. 2024 Jul-Sep;31(3):257-264. doi: 10.4103/jfcm.jfcm_4_24. Epub 2024 Jul 17.
Research has showed a link between patients with methamphetamine dependence and the risk of impulsiveness, aggression, and the risk of suicide. But, this link has not been studied in patients abusing methamphetamine, and it is unknown how impulsiveness, aggression, and the risk of suicide affect them.
This cross-sectional study included 130 adult patients diagnosed with the disorder of the use of amphetamine, methamphetamine, cannabinoids, alcohol, other substances, and polysubstance admitted in the Addiction Department for Mental Health. Participants were interviewed for detailed psychiatric history using a structured questionnaire comprising of structured clinical interview for diagnosis I, Arabic version of the Barratt Impulsiveness Scale-11 (BIS), Beck Scale for Suicidal Ideation for the evaluation of suicidal ideation and behavior, and the Aggression and Hostility scale for adolescents and youth. SPSS was used for data analysis; Initial analysis included descriptive statistics: frequencies and percentages for categorical variables and mean and standard deviation for continuous variables. Chi-square test/Fisher's exact test assessed for association between categorical variables, whereas one-way analysis of variance (ANOVA)/ Kruskal-Wallis test was used to compare continuous variables.
Patients who used methamphetamine either alone (23%) or with polysubstance (42.6%) were associated with higher suicidal risk than patients who did use other substances than methamphetamine (36.1%). A comparison of the three groups on impulsivity, showed significant difference regarding total scores, motor preservation, and non-planning self-control. No significant differences found between three groups on the aggression scores.
There was a higher rate of impulsivity and suicidal risk in patients with methamphetamine dependence in comparison to dependence on other substances, while there was no difference with regard to aggression between patients with methamphetamine dependence and those dependent on other substances. This finding raises the issue of methamphetamine use disorder as a new substance of dependence.
研究表明,甲基苯丙胺依赖患者与冲动、攻击行为及自杀风险之间存在关联。但是,这种关联在滥用甲基苯丙胺的患者中尚未得到研究,而且冲动、攻击行为及自杀风险如何影响他们也尚不清楚。
这项横断面研究纳入了130名成年患者,这些患者被诊断为患有苯丙胺、甲基苯丙胺、大麻素、酒精、其他物质及多种物质使用障碍,入住精神卫生成瘾科。使用一份结构化问卷对参与者进行详细的精神病史访谈,该问卷包括用于诊断的结构化临床访谈I、阿拉伯语版的巴雷特冲动量表-11(BIS)、用于评估自杀观念和行为的贝克自杀观念量表,以及青少年和青年攻击性与敌意量表。使用SPSS进行数据分析;初始分析包括描述性统计:分类变量的频率和百分比,以及连续变量的均值和标准差。卡方检验/费舍尔精确检验用于评估分类变量之间的关联,而单因素方差分析(ANOVA)/克鲁斯卡尔-沃利斯检验用于比较连续变量。
单独使用甲基苯丙胺(23%)或同时使用多种物质(42.6%)的患者自杀风险高于未使用甲基苯丙胺而使用其他物质的患者(36.1%)。对三组在冲动性方面进行比较,结果显示在总分、运动抑制和非计划性自我控制方面存在显著差异。三组在攻击得分方面未发现显著差异。
与依赖其他物质的患者相比,甲基苯丙胺依赖患者的冲动性和自杀风险更高,而甲基苯丙胺依赖患者与依赖其他物质的患者在攻击行为方面没有差异。这一发现提出了甲基苯丙胺使用障碍作为一种新的成瘾物质的问题。