Trull Timothy J, Wycoff Andrea M, Lane Sean P, Carpenter Ryan W, Brown Whitney C
University of Missouri and Midwest Alcoholism Research Center, Columbia, MO, USA.
Research Institute on Addiction, University at Buffalo, State University of New York, Buffalo, NY, USA.
Addiction. 2016 Nov;111(11):2052-2059. doi: 10.1111/add.13471. Epub 2016 Jul 24.
Cannabis and alcohol are the most commonly used (il)licit drugs world-wide. We compared the effects of cannabis and alcohol use on within-person changes in impulsivity, hostility and positive affect at the momentary and daily levels, as they occurred in daily life.
Observational study involving ecological momentary assessments collected via electronic diaries six random times a day for 28 consecutive days.
Out-patients' everyday life contexts in Columbia, MO, USA.
Ninety-three adult psychiatric out-patients (85% female; mean = 30.9 years old) with borderline personality or depressive disorders, who reported using only cannabis (n = 3), only alcohol (n = 58) or both (n = 32) at least once during the study period.
Real-time, standard self-report measures of impulsivity, hostility and positive affect, as impacted by momentary reports of cannabis and alcohol use.
Cannabis use was associated with elevated feelings of impulsivity at the day level [b = 0.83, 95% confidence interval (CI) = 0.17-1.49] and increased hostility at the momentary (b = 0.07, 95% CI = 0.01-0.12) and person (b = 0.81, 95% CI = 0.15-1.47) level. Alcohol use was associated with elevated feelings of impulsivity at the momentary (b = 0.42, 95% CI = 0.13-0.71) and day levels (b = 0.82, 95% CI = 0.22-1.41) and increased positive affect at the momentary (b = 0.12, 95% CI = 0.06-0.18) and day (b = 0.33, 95% CI = 0.16-0.49) levels.
Cannabis and alcohol use are associated with increases in impulsivity (both), hostility (cannabis) and positive affect (alcohol) in daily life, and these effects are part of separate processes that operate on different time-scales (i.e. momentary versus daily).
大麻和酒精是全球最常用的(非)违禁药物。我们比较了大麻和酒精使用对冲动性、敌意和积极情绪在日常生活中瞬间及每日水平的个体内变化的影响。
观察性研究,通过电子日记连续28天每天随机6次进行生态瞬时评估。
美国密苏里州哥伦比亚市门诊患者的日常生活环境。
93名患有边缘型人格或抑郁症的成年精神科门诊患者(85%为女性;平均年龄 = 30.9岁),他们在研究期间报告至少使用过一次大麻(n = 3)、酒精(n = 58)或两者(n = 32)。
受大麻和酒精使用瞬间报告影响的冲动性、敌意和积极情绪的实时、标准自我报告测量。
在日水平上,大麻使用与冲动感增加相关[b = 0.83,95%置信区间(CI)= 0.17 - 1.49],在瞬间(b = 0.07,95% CI = 0.01 - 0.12)和个体水平(b = 0.81,95% CI = 0.15 - 1.47)上与敌意增加相关。酒精使用在瞬间(b = 0.42,95% CI = 0.13 - 0.71)和日水平(b = 0.82,95% CI = 0.22 - 1.41)与冲动感增加相关,在瞬间(b = 0.12,95% CI = 0.06 - 0.18)和日水平(b = 0.33,95% CI = 0.16 - 0.49)与积极情绪增加相关。
大麻和酒精使用与日常生活中冲动性(两者均相关)、敌意(大麻)和积极情绪(酒精)的增加有关,且这些影响是在不同时间尺度(即瞬间与每日)上起作用的不同过程的一部分。