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使用生物发光计对1%和3%次氯酸钠降低乳牙根管内微生物数量的疗效进行比较评估——一项随机临床试验。

Comparative evaluation of the efficacy of 1% and 3% Sodium hypochlorite in reducing the microbial counts in primary teeth root canals using Bioluminometer - A randomized clinical trial.

作者信息

Mukundan Divya, Jeevanandan Ganesh, Vishwanathaiah Satish, Panda Suman, Dawood Tazeen, Abutaleb Aseel, Maganur Prabhadevi C

机构信息

Department of Pediatric and Preventive Dentistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.

Department of Preventive Dental Sciences, Division of Pediatric Dentistry, College of Dentistry, Jazan University, Jazan 45142, Saudi Arabia.

出版信息

Saudi Dent J. 2024 Aug;36(8):1123-1127. doi: 10.1016/j.sdentj.2024.06.006. Epub 2024 Jun 3.

Abstract

PURPOSE

Sodium hypochlorite (NaOCl) is commonly used to irrigate primary teeth during pulpectomy. Although high concentrations of NaOCl are effective, they pose a risk of toxic damage to periapical tissues if NaOCl penetrates through the apical foramen. Therefore, low concentrations of NaOCl are preferred to mitigate this risk. However, concerns persist regarding the antibacterial efficacy of low concentrations of NaOCl compared to high concentrations. The objective of this study was to assess and compare the efficacy of 1% and 3% NaOCl irrigation in reducing bacterial load within primary teeth root canals.

MATERIALS AND METHODS

This clinical study involved forty participants divided into two groups. Group 1 (n = 20) received canal irrigation with 1 % NaOCl solution, while Group 2 (n = 20) received canal irrigation with 3 % NaOCl solution. Microbial samples were collected from the root canal using a paper point before and after irrigation. The samples were aseptically transferred to ultra-snap tubes and then analyzed using a Bioluminometer. The results were recorded.

RESULTS

Both groups exhibited a decrease in bacterial count after irrigation. The mean colony count post irrigation for 3 % NaOCl was 258.05 ± 28.61, and for 1 % NaOCl it was 267.60 ± 30.56. However, no statistically significant difference was observed upon intergroup comparison.

CONCLUSION

This study shows that 1% NaOCl is equally effective as 3% NaOCl in reducing bacterial count in root canals. Thus, using 1% NaOCl as an irrigant is appropriate in clinical practice.

摘要

目的

次氯酸钠(NaOCl)常用于乳牙根管治疗期间的冲洗。虽然高浓度的NaOCl有效,但如果NaOCl通过根尖孔穿透,会对根尖周组织造成毒性损伤风险。因此,为降低此风险,低浓度的NaOCl更受青睐。然而,与高浓度相比,低浓度NaOCl的抗菌效果仍存在担忧。本研究的目的是评估和比较1%和3%的NaOCl冲洗在降低乳牙根管内细菌载量方面的效果。

材料与方法

本临床研究纳入40名参与者,分为两组。第1组(n = 20)接受1% NaOCl溶液根管冲洗,而第2组(n = 20)接受3% NaOCl溶液根管冲洗。冲洗前后使用纸尖从根管收集微生物样本。样本无菌转移至超低温冻存管,然后使用生物发光计进行分析。记录结果。

结果

两组冲洗后细菌计数均下降。3% NaOCl冲洗后的平均菌落计数为258.05 ± 28.61,1% NaOCl冲洗后的平均菌落计数为267.60 ± 30.56。然而,组间比较未观察到统计学显著差异。

结论

本研究表明,1% NaOCl在降低根管内细菌计数方面与3% NaOCl同样有效。因此,在临床实践中使用1% NaOCl作为冲洗剂是合适的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0994/11337955/993fc185cb3f/gr1.jpg

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