高水平隔离单元在应对高后果和新发传染病中的作用：德国 STAKOB 网络的经验。
The Role of High-Level Isolation Units in Response to High-Consequence and Emerging Infectious Diseases: Experience of the German STAKOB Network.
机构信息
Michaela Niebank, MD, is Head, Clinical Management and Infection Control, and Head, STAKOB office; and Agata Mikolajewska, MD, is a Staff Member and Coordinator, STAKOB office; both at the Center for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany. Stefan O. Brockmann, MD, is Head, Landesgesundheitsamt Referat 73, Ministerium für Soziales, Gesundheit und Integration Baden-Württemberg, Stuttgart, Germany. Torsten Feldt, MD, DTM, is an Infectious Disease Physician, Professor, and Head, Tropical Medicine Unit, Department of Gastroenterology, Hepatology and Infectious Diseases, Düsseldorf University Hospital, and Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. Björn-Erik Ole Jensen, MD, PD, DTM, is Coordinator, High-Level Isolation Unit, Department of Gastroenterology, Hepatology and Infectious Diseases, Düsseldorf University Hospital, and Medical Faculty, Heinrich Heine University, Düsseldorf, Germany. Annette Jurke, PD, MSc, is Speaker, STAKOB, and Head; and Jennifer Schauer, PhD, is a Staff Member; both in the Infectious Disease Epidemiology Section, NRW Centre for Health, Bochum, Germany. Katja Rothfuss, MD, is Coordinator High-Level Isolation Unit, Department of Gastroenterology, Hepatology and Endocrinology, Robert-Bosch-Hospital, Stuttgart, Germany. Stefan Schmiedel, MD, PhD, DTMPH, is a Consultant, Infectious Disease and Tropical Medicine, and Coordinator, High Level Isolation Unit, University Medical Center Hamburg Eppendorf (UKE), Hamburg, Germany. Miriam Stegemann, MD, DTMH, is Head, Infectiology, Campus Virchow-Klinikum, Head of Antibiotic Stewardship, Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. Peter Tinnemann, MD, PD, MPH, is Head, Gesundheitsamt Frankfurt, Frankfurt am Main, Germany. Alexander Uhrig, MD, is Medical Director, Medical Intensive Care Unit/High-level Isolation Unit, Department of Infectious Diseases and Respiratory Medicine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. Timo Wolf, MD, PD, DTM, is Speaker, STAKOB, and Head, High-level Isolation Unit, Internal Medicine, Infectious Diseases, University Hospital, Goethe University Frankfurt, Frankfurt, Germany.
出版信息
Health Secur. 2024 Sep;22(S1):S97-S103. doi: 10.1089/hs.2023.0156. Epub 2024 Aug 23.
This case study describes the experience of the German Permanent Working Group of Competence and Treatment Centers for High Consequence Infectious Diseases, known as STAKOB (). STAKOB brings together public health authorities (competence centers) and high-level isolation units (treatment centers) to collaborate on the clinical management of high-consequence infectious diseases (HCIDs) and emerging infectious diseases. The network is coordinated by the Robert Koch Institute, Germany's federal public health institute. The main tasks of STAKOB are to strengthen HCID clinical and public health management and increase expert knowledge on HCID and non-HCID emerging infectious diseases in Germany. STAKOB enables the exchange of knowledge and experiences; development of guidelines on infection prevention and control measures, clinical management, and therapy; and support for the World Health Organization and other outbreak responses internationally. The past years have shown how important the STAKOB network is for Germany-not only in providing critical care for HCID cases but also increasing capacity to support public health and clinical management of emerging infectious disease cases. However, maintaining several high-level isolation units in Germany requires a high commitment of financial, material, and human resources. Due to the rarity of HCID and emerging infectious disease events, maintaining the appropriate level of preparedness and ensuring sufficient investments is an ongoing struggle. Nevertheless, it is essential to have a network ready to react to HCID and non-HCID emerging infectious diseases in times of a changing biosecurity and infectious landscape.
本案例研究介绍了德国高后果传染病能力和治疗中心常设工作组（简称 STAKOB）的经验。STAKOB 将公共卫生当局（能力中心）和高级别隔离单位（治疗中心）聚集在一起，共同管理高后果传染病（HCID）和新发传染病。该网络由德国联邦公共卫生研究所罗伯特·科赫研究所协调。STAKOB 的主要任务是加强 HCID 的临床和公共卫生管理，并增加德国对 HCID 和非 HCID 新发传染病的专业知识。STAKOB 能够促进知识和经验的交流；制定感染预防和控制措施、临床管理和治疗方面的指南；并支持世界卫生组织和其他国际疫情应对。过去几年表明，STAKOB 网络对德国非常重要——不仅为 HCID 病例提供了重症护理，还提高了支持新发传染病病例的公共卫生和临床管理能力。然而，在德国维持多个高级别隔离单位需要大量的财政、物质和人力资源投入。由于 HCID 和新发传染病事件的罕见性，维持适当的准备水平并确保充足的投资是一项持续的挑战。尽管如此，在生物安全和传染病形势不断变化的情况下，建立一个随时准备应对 HCID 和非 HCID 新发传染病的网络是至关重要的。
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