Student Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran; Neurosciences Research Center (NSRC), Tabriz University of Medical Sciences, Tabriz, Iran.
Department of Clinical Nutrition and Dietetics, Faculty of Nutrition Sciences and Food Technology, National Nutrition and Food Technology Research Institute, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Clin Nutr ESPEN. 2024 Dec;64:37-43. doi: 10.1016/j.clnesp.2024.08.013. Epub 2024 Aug 22.
Coffee and tea are considered to have some effects on the risk of glioma as one of the most prevalent intracranial malignant tumors in adults. However, the precise effect of coffee and tea consumption on glioma is not obvious. This umbrella review aimed to evaluate the impact of tea and coffee consumption on glioma risk.
Three online databases containing Scopus, Web of Science, and PubMed were thoroughly searched from the beginning to February 23, 2024 with no language constraints. Relying on I and Q statistics, a random-effect model or a fixed-effect model was applied. The PICO structure was followed as Population (Patients with glioma), Intervention (Coffee and tea consumption), Comparison (Standard treatment or placebo), and Outcome (Risk of glioma).
Totally, seven meta-analyses and systematic reviews contain 23,591 patients were included in this umbrella review. Coffee and tea consumption led to significant 15% and 16% reductions in glioma risk, respectively (RR = 0.85; 95% CI: 0.74, 0.98; RR = 0.84; 95% CI: 0.79, 0.89). The results did not change after subgroup analyses.
This umbrella review revealed that the coffee and tea consumption may decrease the glioma risk. Consumption of tea and coffee may be considered as dietary strategies against glioma.
CRD42024521525.
咖啡和茶被认为对胶质瘤风险有一定影响，胶质瘤是成人中最常见的颅内恶性肿瘤之一。然而，咖啡和茶的消耗对胶质瘤的确切影响并不明显。本伞状评价旨在评估茶和咖啡消耗对胶质瘤风险的影响。
从 2024 年 2 月 23 日开始，我们彻底搜索了包含 Scopus、Web of Science 和 PubMed 的三个在线数据库，无语言限制。基于 I²和 Q 统计，应用随机效应模型或固定效应模型。遵循 PICO 结构，即人群（胶质瘤患者）、干预（咖啡和茶消耗）、比较（标准治疗或安慰剂）和结局（胶质瘤风险）。
共有 7 项荟萃分析和系统评价纳入了本伞状评价，共包含 23591 名患者。咖啡和茶的消耗分别导致胶质瘤风险显著降低 15%和 16%（RR=0.85；95%CI：0.74，0.98；RR=0.84；95%CI：0.79，0.89）。亚组分析后结果没有变化。
本伞状评价表明，咖啡和茶的消耗可能降低胶质瘤风险。茶和咖啡的消耗可被视为针对胶质瘤的饮食策略。
PROSPERO 注册号：CRD42024521525。
