有证据表明，乳糖操纵子mRNA的5'端一合成便开始衰变。
Evidence that the 5' end of lac mRNA starts to decay as soon as it is synthesized.
作者信息
Cannistraro V J, Kennell D
出版信息
J Bacteriol. 1985 Feb;161(2):820-2. doi: 10.1128/jb.161.2.820-822.1985.
Abstract
By monitoring the decay of the first 16% of the beta-galactosidase message, we showed that the 5' end started to decay before the 3' end was completed and at a rate equivalent to that of the whole molecule. Thus, decay was neither from 3' to 5' nor from random internal fragmentation but rather proceeded in a net 5' to 3' direction.
摘要
通过监测β-半乳糖苷酶信息前16%的衰减情况，我们发现5'端在3'端完成之前就开始衰减，且衰减速率与整个分子的衰减速率相当。因此，衰减既不是从3'到5'，也不是随机的内部片段化，而是以净5'到3'的方向进行。
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